PBXIP1 and DEF6

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

		PBXIP1	DEF6
Description		PBX homeobox interacting protein 1	DEF6 guanine nucleotide exchange factor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Microtubule Membrane	Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton Plasma Membrane Membrane Filopodium Perinuclear Region Of Cytoplasm
	Molecular Function	Transcription Corepressor Activity Protein Binding	Protein Binding
	Biological Process	Multicellular Organism Development Cell Differentiation Negative Regulation Of Transcription, DNA-templated Regulation Of Rho Guanyl-nucleotide Exchange Factor Activity
Pathways
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Inflammatory bowel disease ( 27569725) Prostate cancer ( 23535732)	Height ( 18391951) Systemic lupus erythematosus ( 28714469)
Interacting Genes		22 interacting genes: BRPF1 CAPN2 CCDC85B CCNC DAXX DEF6 DPPA2 ESR1 GMCL1 GRB2 MDFI MDM2 MORF4L1 PCBD2 PRKAA2 SGTA TSNAX UBQLN1 UBQLN4 WASHC3 ZMYND8 ZZZ3	15 interacting genes: APP BEGAIN CDC42 CDC42EP1 EIF4ENIF1 HOMEZ LCK PBXIP1 PLSCR1 PTK2 RAC1 RAC2 RHOA TCF4 ZAP70
Entrez ID		57326	50619
HPRD ID		17823	10869
Ensembl ID		ENSG00000163346	ENSG00000023892
Uniprot IDs		B4E0K4 Q96AQ6	Q9H4E7
PDB IDs
Enriched GO Terms of Interacting Partners?
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