CMTM5 and GAD1

Number of citations of the paper that reports this interaction (PubMedID 26871637)
108

Data Source:
BioGRID (two hybrid, two hybrid)

		CMTM5	GAD1
Description		CKLF like MARVEL transmembrane domain containing 5	glutamate decarboxylase 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Integral Component Of Membrane	Plasma Membrane Cell Cortex Vesicle Membrane Axon Terminus Presynaptic Active Zone Inhibitory Synapse Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane
	Molecular Function	Cytokine Activity Protein Binding	Glutamate Decarboxylase Activity Protein Binding Glutamate Binding Pyridoxal Phosphate Binding Protein-containing Complex Binding Protein N-terminus Binding
	Biological Process	Chemotaxis Signal Transduction Negative Regulation Of Myoblast Differentiation	Glutamate Catabolic Process Glutamate Decarboxylation To Succinate Chemical Synaptic Transmission Neurotransmitter Secretion Gamma-aminobutyric Acid Biosynthetic Process Protein-pyridoxal-5-phosphate Linkage Social Behavior Locomotory Exploration Behavior Response To Drug
Pathways			GABA synthesis GABA synthesis, release, reuptake and degradation MECP2 regulates transcription of genes involved in GABA signaling
Drugs			Pyridoxal Phosphate Pyridoxal Phosphate Pyridoxal Phosphate Glutamic Acid
Diseases			Cerebral palsy
GWAS			Menopause (age at onset) ( 26414677)
Interacting Genes		54 interacting genes: AACS ACSF2 ALDH18A1 APOA1 ARMC9 COQ8A CPLX1 CREB3 CYP1A1 DDA1 ECPAS FAM114A1 FARS2 FERMT2 GAD1 GAD2 GLTP GOLGA2P10 GTF3C1 HNRNPK LMNA LMO2 MCEE MTERF3 MYG1 NDRG4 PIMREG PITPNC1 PLIN3 PNPO PPIF PPP2R3C PTPN9 RBFA RMDN2 RNF185 RSRC2 SDCBP SH3GLB1 SHMT2 SNX1 SPATA8 SPG21 SSX3 SUCLA2 SYNE4 TIMM44 TPD52L3 TTPA TUBB TUFM VARS2 ZNF391 ZNF599	15 interacting genes: AGTRAP CMTM5 GAD2 HAAO KRT31 KRT40 KRTAP3-2 MAL2 PPP2CA PPP2CB PRKACA PRKCE STK3 TRIM23 TRIP6
Entrez ID		116173	2571
HPRD ID		06986	12011
Ensembl ID		ENSG00000166091	ENSG00000128683
Uniprot IDs		Q96DZ9	A0A0S2Z3V5 Q8IVA8 Q99259
PDB IDs			2OKJ 3VP6
Enriched GO Terms of Interacting Partners?
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