CMTM5 and SUCLA2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, two hybrid)

		CMTM5	SUCLA2
Description		CKLF like MARVEL transmembrane domain containing 5	succinate-CoA ligase ADP-forming subunit beta
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Integral Component Of Membrane	Mitochondrion Mitochondrial Matrix Succinate-CoA Ligase Complex Extracellular Exosome
	Molecular Function	Cytokine Activity Protein Binding	Magnesium Ion Binding Succinate-CoA Ligase (ADP-forming) Activity Protein Binding ATP Binding
	Biological Process	Chemotaxis Signal Transduction Negative Regulation Of Myoblast Differentiation	Tricarboxylic Acid Cycle Succinyl-CoA Metabolic Process Succinate Metabolic Process Succinyl-CoA Pathway
Pathways			Citric acid cycle (TCA cycle)
Drugs			Succinic acid
Diseases			Mitochondrial DNA depletion syndrome (MDS)
GWAS			Aging (time to event) ( 21782286) Colorectal cancer (diet interaction) ( 24743840) Thiopurine-induced acute severe leukopenia in inflammatory bowel disease ( 29923122) Thiopurine-induced alopecia in inflammatory bowel disease ( 29923122) Thiopurine-induced early leukopenia in Crohn's disease ( 25108385) Thiopurine-induced leukopenia in inflammatory bowel disease ( 29923122) Thiopurine-induced severe alopecia in inflammatory bowel disease ( 29923122) Thiopurine-induced severe leukopenia in inflammatory bowel disease ( 29923122) Visceral adipose tissue adjusted for BMI ( 22589738) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Interacting Genes		54 interacting genes: AACS ACSF2 ALDH18A1 APOA1 ARMC9 COQ8A CPLX1 CREB3 CYP1A1 DDA1 ECPAS FAM114A1 FARS2 FERMT2 GAD1 GAD2 GLTP GOLGA2P10 GTF3C1 HNRNPK LMNA LMO2 MCEE MTERF3 MYG1 NDRG4 PIMREG PITPNC1 PLIN3 PNPO PPIF PPP2R3C PTPN9 RBFA RMDN2 RNF185 RSRC2 SDCBP SH3GLB1 SHMT2 SNX1 SPATA8 SPG21 SSX3 SUCLA2 SYNE4 TIMM44 TPD52L3 TTPA TUBB TUFM VARS2 ZNF391 ZNF599	6 interacting genes: AGTRAP ALAS2 ARL6IP1 CMTM5 FAM9B MTNR1A
Entrez ID		116173	8803
HPRD ID		06986	06798
Ensembl ID		ENSG00000166091	ENSG00000136143
Uniprot IDs		Q96DZ9	E5KS60 Q9P2R7 Q9Y4T0
PDB IDs			6G4Q
Enriched GO Terms of Interacting Partners?
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