IRS2 and SOCS3

  • Number of citations of the paper that reports this interaction (PubMedID 15514089)
  • 6
  • Data Source:
  • HPRD (in vivo)

IRS2

SOCS3

Description insulin receptor substrate 2 suppressor of cytokine signaling 3
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Blood trace element (Se levels) ( 23720494)
  • Creatine kinase levels ( 29403010)
Interacting Genes 40 interacting genes: ATP2A1 ATP2A2 BCL2L1 CRK EPOR FES GRB2 IGF1R IL4R INSR JAK1 JAK2 JAK3 MPL MTDH NEDD4 NTRK1 PIK3CA PIK3CD PIK3R1 PIK3R2 PIK3R3 PLCG1 PTPN11 PTPN6 PTPRF RPTOR SHC1 SOCS1 SOCS3 SOCS6 SOCS7 SRPK2 TYK2 UBTF YWHAB YWHAE YWHAG YWHAQ YWHAZ 54 interacting genes: ABL1 ACADVL APP BCL10 BIK CSF1R CSF3R CSNK1E CUEDC2 CXCR4 EGFR ELOB ELOC EPOR GFRA1 GHR HIVEP1 IGF1R IL12RB2 IL2RB IL6ST INSR IRF7 IRS1 IRS2 JAK1 JAK2 JAK3 KIAA1958 LEPR MAP1S MAPK11 MAPK6 NME4 PDPK1 PIN1 PPP3CB PRLR PTK2 PTPN11 RASA1 RBMX RNF31 RNF7 RPL7A SH2D2A SOCS2 TES TFDP1 TFR2 TRDN TXNDC11 YES1 YWHAQ
Entrez ID 8660 9021
HPRD ID 02878 05006
Ensembl ID ENSG00000185950 ENSG00000184557
Uniprot IDs Q9P084 Q9Y4H2 O14543 Q6FI39
PDB IDs 3FQW 3FQX
Enriched GO Terms of Interacting Partners?
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