PRKRA and ZMAT3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		PRKRA	ZMAT3
Description		protein activator of interferon induced protein kinase EIF2AK2	zinc finger matrin-type 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Membrane Perinuclear Region Of Cytoplasm RISC-loading Complex	Nucleoplasm Nucleolus Plasma Membrane
	Molecular Function	RNA Binding Double-stranded RNA Binding Protein Binding Enzyme Activator Activity Enzyme Binding Identical Protein Binding Protein Homodimerization Activity Pre-miRNA Binding	RNA Binding Protein Binding Zinc Ion Binding
	Biological Process	Protein Phosphorylation Immune Response Negative Regulation Of Cell Proliferation Response To Virus MiRNA Metabolic Process Viral Process Production Of SiRNA Involved In RNA Interference Pre-miRNA Processing Cellular Response To Oxidative Stress Production Of MiRNAs Involved In Gene Silencing By MiRNA Outer Ear Morphogenesis Middle Ear Morphogenesis Positive Regulation Of Catalytic Activity Skeletal System Morphogenesis Protein Stabilization Positive Regulation Of Intrinsic Apoptotic Signaling Pathway	Apoptotic Process Cellular Response To DNA Damage Stimulus Protein Transport Regulation Of Growth Positive Regulation Of Apoptotic Process
Pathways		MicroRNA (miRNA) biogenesis Small interfering RNA (siRNA) biogenesis
Drugs
Diseases		Primary torsion dystonia (PTD)
GWAS		Inflammatory skin disease ( 25574825) Multiple sclerosis (OCB status) ( 23472185) Rapid functional decline in sporadic amyotrophic lateral sclerosis ( 26746183)	Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Metabolite levels ( 23823483) Platelet count ( 27863252) Post-traumatic stress disorder (asjusted for relatedness) ( 23726511)
Interacting Genes		21 interacting genes: AGO2 CEBPZ CEP126 COPS6 DICER1 EIF2AK2 GDF9 LYAR NKRF POLR2G RABEPK RB1 SETDB1 SHC1 SNX5 TARBP2 TIRAP TP53 ZFP28 ZMAT3 ZNF746	5 interacting genes: APP PRKRA SIAH1 STAU1 SUMO2
Entrez ID		8575	64393
HPRD ID		04573	07343
Ensembl ID		ENSG00000180228	ENSG00000172667
Uniprot IDs		B4DJC7 O75569	Q9HA38
PDB IDs		2DIX
Enriched GO Terms of Interacting Partners?
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