PRKRA and NKRF

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		PRKRA	NKRF
Description		protein activator of interferon induced protein kinase EIF2AK2	NFKB repressing factor
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Membrane Perinuclear Region Of Cytoplasm RISC-loading Complex	Nucleus Nucleoplasm Nucleolus
	Molecular Function	RNA Binding Double-stranded RNA Binding Protein Binding Enzyme Activator Activity Enzyme Binding Identical Protein Binding Protein Homodimerization Activity Pre-miRNA Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific RNA Binding Protein Binding
	Biological Process	Protein Phosphorylation Immune Response Negative Regulation Of Cell Proliferation Response To Virus MiRNA Metabolic Process Viral Process Production Of SiRNA Involved In RNA Interference Pre-miRNA Processing Cellular Response To Oxidative Stress Production Of MiRNAs Involved In Gene Silencing By MiRNA Outer Ear Morphogenesis Middle Ear Morphogenesis Positive Regulation Of Catalytic Activity Skeletal System Morphogenesis Protein Stabilization Positive Regulation Of Intrinsic Apoptotic Signaling Pathway	Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II
Pathways		MicroRNA (miRNA) biogenesis Small interfering RNA (siRNA) biogenesis
Drugs
Diseases		Primary torsion dystonia (PTD)
GWAS		Inflammatory skin disease ( 25574825) Multiple sclerosis (OCB status) ( 23472185) Rapid functional decline in sporadic amyotrophic lateral sclerosis ( 26746183)
Interacting Genes		21 interacting genes: AGO2 CEBPZ CEP126 COPS6 DICER1 EIF2AK2 GDF9 LYAR NKRF POLR2G RABEPK RB1 SETDB1 SHC1 SNX5 TARBP2 TIRAP TP53 ZFP28 ZMAT3 ZNF746	8 interacting genes: DHX58 HMOX2 KIFC1 NFKB1 NFKB2 PRKRA REL RELA
Entrez ID		8575	55922
HPRD ID		04573	02341
Ensembl ID		ENSG00000180228	ENSG00000186416
Uniprot IDs		B4DJC7 O75569	A3F769 O15226
PDB IDs		2DIX
Enriched GO Terms of Interacting Partners?
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