ZMAT3 and PRKRA

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		ZMAT3	PRKRA
Description		zinc finger matrin-type 3	protein activator of interferon induced protein kinase EIF2AK2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Plasma Membrane	Nucleoplasm Cytoplasm Cytosol Membrane Perinuclear Region Of Cytoplasm RISC-loading Complex
	Molecular Function	RNA Binding Protein Binding Zinc Ion Binding	RNA Binding Double-stranded RNA Binding Protein Binding Enzyme Activator Activity Enzyme Binding Identical Protein Binding Protein Homodimerization Activity Pre-miRNA Binding
	Biological Process	Apoptotic Process Cellular Response To DNA Damage Stimulus Protein Transport Regulation Of Growth Positive Regulation Of Apoptotic Process	Protein Phosphorylation Immune Response Negative Regulation Of Cell Proliferation Response To Virus MiRNA Metabolic Process Viral Process Production Of SiRNA Involved In RNA Interference Pre-miRNA Processing Cellular Response To Oxidative Stress Production Of MiRNAs Involved In Gene Silencing By MiRNA Outer Ear Morphogenesis Middle Ear Morphogenesis Positive Regulation Of Catalytic Activity Skeletal System Morphogenesis Protein Stabilization Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways			MicroRNA (miRNA) biogenesis Small interfering RNA (siRNA) biogenesis
Drugs
Diseases			Primary torsion dystonia (PTD)
GWAS		Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Metabolite levels ( 23823483) Platelet count ( 27863252) Post-traumatic stress disorder (asjusted for relatedness) ( 23726511)	Inflammatory skin disease ( 25574825) Multiple sclerosis (OCB status) ( 23472185) Rapid functional decline in sporadic amyotrophic lateral sclerosis ( 26746183)
Interacting Genes		5 interacting genes: APP PRKRA SIAH1 STAU1 SUMO2	21 interacting genes: AGO2 CEBPZ CEP126 COPS6 DICER1 EIF2AK2 GDF9 LYAR NKRF POLR2G RABEPK RB1 SETDB1 SHC1 SNX5 TARBP2 TIRAP TP53 ZFP28 ZMAT3 ZNF746
Entrez ID		64393	8575
HPRD ID		07343	04573
Ensembl ID		ENSG00000172667	ENSG00000180228
Uniprot IDs		Q9HA38	B4DJC7 O75569
PDB IDs			2DIX
Enriched GO Terms of Interacting Partners?
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