PPFIA3 and PTPRU

Number of citations of the paper that reports this interaction (PubMedID 9624153)
84

Data Source:
HPRD (in vitro)

		PPFIA3	PTPRU
Description		PTPRF interacting protein alpha 3	protein tyrosine phosphatase receptor type U
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Cytosol Presynaptic Active Zone Presynaptic Active Zone Cytoplasmic Component Epididymosome Glutamatergic Synapse	Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction
	Molecular Function	Protein Binding	Protein Tyrosine Phosphatase Activity Transmembrane Receptor Protein Tyrosine Phosphatase Activity Protein Binding Beta-catenin Binding
	Biological Process	Neurotransmitter Secretion Glutamate Secretion Synaptic Vesicle Docking Regulation Of Short-term Neuronal Synaptic Plasticity Synapse Organization	Protein Dephosphorylation Cell Adhesion Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Negative Regulation Of Cell Proliferation Cell Differentiation Negative Regulation Of Cell Migration Animal Organ Regeneration Homotypic Cell-cell Adhesion Protein Localization To Cell Surface Peptidyl-tyrosine Dephosphorylation Response To Glucocorticoid Negative Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Cell-cell Adhesion Mediated By Cadherin
Pathways		Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle Receptor-type tyrosine-protein phosphatases	Signaling by SCF-KIT
Drugs
Diseases
GWAS			Bipolar disorder and schizophrenia ( 20889312) Blood protein levels ( 30072576) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Pediatric non-alcoholic fatty liver disease activity score ( 23535911) Schizophrenia ( 28991256) Tourette syndrome ( 30818990)
Interacting Genes		11 interacting genes: CAST ERC2 GIT1 PPFIA1 PPFIA2 PPFIBP1 PPFIBP2 PTPRD PTPRF PTPRS PTPRU	10 interacting genes: CTNNB1 EGFR ERBB2 GNAI1 GNAI2 GNAI3 GNAO1 IRS1 KIT PPFIA3
Entrez ID		8541	10076
HPRD ID		04393	03908
Ensembl ID		ENSG00000177380	ENSG00000060656
Uniprot IDs		O75145	Q92729
PDB IDs
Enriched GO Terms of Interacting Partners?
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