PPP1R15B and RAD21

Number of citations of the paper that reports this interaction (PubMedID 22145905)
9

Data Source:
BioGRID (two hybrid)

		PPP1R15B	RAD21
Description		protein phosphatase 1 regulatory subunit 15B	RAD21 cohesin complex component
Image		No pdb structure
GO Annotations	Cellular Component	Protein Phosphatase Type 1 Complex Cytoplasm Endoplasmic Reticulum	Chromosome, Centromeric Region Chromatin Nuclear Cohesin Complex Spindle Pole Nucleoplasm Chromosome Cytosol Cohesin Complex Membrane Nuclear Matrix Meiotic Cohesin Complex
	Molecular Function	Protein Binding Protein Phosphatase Regulator Activity	Chromatin Binding Protein Binding
	Biological Process	Negative Regulation Of Protein Phosphorylation ER Overload Response Positive Regulation Of Phosphoprotein Phosphatase Activity Response To Endoplasmic Reticulum Stress Response To Hydrogen Peroxide Peptidyl-serine Dephosphorylation Negative Regulation Of PERK-mediated Unfolded Protein Response Negative Regulation Of Endoplasmic Reticulum Stress-induced EIF2 Alpha Phosphorylation	Double-strand Break Repair DNA Recombination Regulation Of Transcription By RNA Polymerase II Apoptotic Process Sister Chromatid Cohesion Reciprocal Meiotic Recombination Multicellular Organism Development Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Mitotic Metaphase/anaphase Transition Positive Regulation Of Sister Chromatid Cohesion Cell Division Meiotic Cell Cycle Protein Localization To Chromatin
Pathways			Meiotic synapsis Separation of Sister Chromatids Establishment of Sister Chromatid Cohesion Cohesin Loading onto Chromatin Resolution of Sister Chromatid Cohesion SUMOylation of DNA damage response and repair proteins Estrogen-dependent gene expression
Drugs
Diseases
GWAS		Prostate cancer ( 23535732) Regular attendance at a religious group ( 29970889)	Menopause (age at onset) ( 29773799)
Interacting Genes		3 interacting genes: PPP1CA PPP1CC RAD21	28 interacting genes: CAPN1 CASP7 CFL1 CSTB DISC1 DYNLT1 FHL3 FLNB HNRNPH2 IL7R MSRB2 MT-CO2 NUMA1 PPP1R15A PPP1R15B RPL10 RPL13 RPL35A SMARCA5 SMC1A SSU72 STAG1 STAG2 TMSB4X TNFRSF14 WAPL WNT2B ZNF80
Entrez ID		84919	5885
HPRD ID		17892	05924
Ensembl ID		ENSG00000158615	ENSG00000164754
Uniprot IDs			A0A024R9J0 O60216
PDB IDs			4PJU 4PJW 4PK7 6RRC 6RRK
Enriched GO Terms of Interacting Partners?
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