GEMIN2 and SNRPN

Number of citations of the paper that reports this interaction (PubMedID 28514442)
199

Data Source:
BioGRID (affinity chromatography technology, pull down)

		GEMIN2	SNRPN
Description		gem nuclear organelle associated protein 2	small nuclear ribonucleoprotein polypeptide N
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Nucleolus Cytoplasm Cytosol Nuclear Body SMN Complex SMN-Sm Protein Complex Gemini Of Coiled Bodies	Nucleoplasm Spliceosomal Complex U5 SnRNP U1 SnRNP U2 SnRNP U4 SnRNP Cytoplasm Small Nuclear Ribonucleoprotein Complex U4/U6 X U5 Tri-snRNP Complex U2-type Prespliceosome Catalytic Step 2 Spliceosome
	Molecular Function	Protein Binding	RNA Binding Protein Binding
	Biological Process	Spliceosomal Complex Assembly RNA Splicing, Via Transesterification Reactions Spliceosomal SnRNP Assembly MRNA Processing RNA Splicing Import Into Nucleus	MRNA Splicing, Via Spliceosome RNA Splicing Response To Hormone
Pathways		snRNP Assembly	mRNA Splicing - Major Pathway
Drugs
Diseases			Prader-Willi and Angelman syndromes, including: Angelman syndrome (AS); Prader-Willi syndrome (PWS)
GWAS		Vitamin D levels ( 28757204)	Aspartate aminotransferase levels ( 31219225) Carotid plaque burden ( 28282560) Cerebrospinal fluid t-tau:AB1-42 ratio ( 30153862) Obesity-related traits ( 23251661) Panic disorder ( 31712720) Periodontal disease related phenotype (PCT5) ( 26962152) Periodontitis (DPAL) ( 24024966) Pulmonary function ( 17903307)
Interacting Genes		24 interacting genes: DDX20 DHX9 FBXO7 GEMIN5 IKBKG MTNR1A NUFIP1 RN7SL1 RNU1-1 RNU2-1 SMN1 SMN2 SNRNP70 SNRPD1 SNRPD2 SNRPD3 SNRPN SRSF1 SRSF2 SRSF3 SRSF4 STXBP2 STXBP3 U2AF2	11 interacting genes: ARL4D CTBP1 FBL GEMIN2 GTF2I KEAP1 LRIF1 MAFG RBFOX1 SH3GL3 TP53
Entrez ID		8487	6638
HPRD ID		03999	01653
Ensembl ID		ENSG00000092208	ENSG00000128739
Uniprot IDs		O14893	P63162 X5DP00
PDB IDs		2LEH 5XJL 5XJQ 5XJR 5XJS 5XJT 5XJU	5MF9
Enriched GO Terms of Interacting Partners?
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