GEMIN2 and DDX20

Number of citations of the paper that reports this interaction (PubMedID 10601333)
85

Data Source:
HPRD (in vitro, in vivo)

		GEMIN2	DDX20
Description		gem nuclear organelle associated protein 2	DEAD-box helicase 20
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Nucleolus Cytoplasm Cytosol Nuclear Body SMN Complex SMN-Sm Protein Complex Gemini Of Coiled Bodies	Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton Membrane SMN Complex SMN-Sm Protein Complex RNA Polymerase II Transcription Repressor Complex Gemini Of Coiled Bodies
	Molecular Function	Protein Binding	DNA Binding RNA Binding RNA Helicase Activity Protein Binding ATP Binding Protein Domain Specific Binding Protein Binding, Bridging Histone Deacetylase Binding Repressing Transcription Factor Binding
	Biological Process	Spliceosomal Complex Assembly RNA Splicing, Via Transesterification Reactions Spliceosomal SnRNP Assembly MRNA Processing RNA Splicing Import Into Nucleus	Negative Regulation Of Transcription By RNA Polymerase II Spliceosomal Tri-snRNP Complex Assembly Spliceosomal SnRNP Assembly RNA Processing Negative Regulation Of Cell Proliferation Positive Regulation Of Apoptotic Process Oogenesis Regulation Of Steroid Biosynthetic Process Import Into Nucleus
Pathways		snRNP Assembly	snRNP Assembly
Drugs
Diseases
GWAS		Vitamin D levels ( 28757204)	Body mass index ( 29273807) Metabolite levels ( 23823483)
Interacting Genes		24 interacting genes: DDX20 DHX9 FBXO7 GEMIN5 IKBKG MTNR1A NUFIP1 RN7SL1 RNU1-1 RNU2-1 SMN1 SMN2 SNRNP70 SNRPD1 SNRPD2 SNRPD3 SNRPN SRSF1 SRSF2 SRSF3 SRSF4 STXBP2 STXBP3 U2AF2	33 interacting genes: AGO2 APP CRYAB DHX9 ETV3 GEMIN2 GEMIN4 GEMIN5 HDAC2 HDAC5 LSM2 NCOR1 NCOR2 NR0B2 NUFIP1 PRRC2A RN7SL1 RNU1-1 RNU2-1 SIN3A SMN1 SMN2 SNRPB SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG SNUPN STXBP2 STXBP3 TP53
Entrez ID		8487	11218
HPRD ID		03999	05859
Ensembl ID		ENSG00000092208	ENSG00000064703
Uniprot IDs		O14893	Q9H4N4 Q9UHI6
PDB IDs		2LEH 5XJL 5XJQ 5XJR 5XJS 5XJT 5XJU	2OXC 3B7G
Enriched GO Terms of Interacting Partners?
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