SETD1A

Description		SET domain containing 1A, histone lysine methyltransferase
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GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Nuclear Speck Histone Methyltransferase Complex Set1C/COMPASS Complex
	Molecular Function	RNA Binding Protein Binding Beta-catenin Binding Transcription Factor Binding Histone Methyltransferase Activity (H3-K4 Specific)
	Biological Process	Histone H3-K4 Dimethylation Regulation Of Megakaryocyte Differentiation Histone H3-K4 Trimethylation Histone H3-K4 Monomethylation Regulation Of Hematopoietic Stem Cell Differentiation Regulation Of Chromatin Organization
Pathways		PKMTs methylate histone lysines RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
Drugs
Diseases
GWAS		Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Mean corpuscular hemoglobin ( 27863252) Multiple sclerosis ( 31604244) Parkinson's disease ( 31660654) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)
Interacting Genes		6 interacting genes: BCKDK DPY30 EP300 H3C1 H3C14 LBP
Entrez ID		9739
HPRD ID		13795
Ensembl ID		ENSG00000099381
Uniprot IDs		O15047
PDB IDs		3S8S 3UVN 4EWR
Enriched GO Terms of Interacting Partners?
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