NCK2 and DOCK1

  • Number of citations of the paper that reports this interaction (PubMedID 11240126)
  • 13
  • Data Source:
  • HPRD (in vitro, two hybrid, in vivo)

NCK2

DOCK1

Description NCK adaptor protein 2 dedicator of cytokinesis 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Addiction ( 23533358)
  • Platelet distribution width ( 27863252)
  • Systolic blood pressure in sickle cell anemia ( 24058526)
  • Airway wall thickness ( 25517131)
  • Apolipoprotein Levels ( 23031429)
  • Body mass index ( 25673413)
  • Body mass index (change over time) in gastrointestinal cancer ( 28044437)
  • Body mass index (change over time) in gastrointestinal cancer or chronic obstructive pulmonary disease ( 28044437)
  • BRCA1/2-negative high-risk breast cancer ( 30323354)
  • Chronotype ( 30696823)
  • Homeostasis model assessment of insulin resistance in less-fat diet ( 30327367)
  • Response to cytidine analogues (gemcitabine) ( 24483146)
  • Response to TNF inhibitor in rheumatoid arthritis (change in disease activity score) ( 30166627)
  • Response to TNF inhibitor in rheumatoid arthritis (change in tender 28-joint count) ( 30166627)
  • Social communication problems ( 24564958)
  • Weight ( 28552196)
Interacting Genes 87 interacting genes: ABI1 ABI2 ABI3 ARHGAP32 ATN1 AXIN1 AXL BCL11A CBLB CCDC33 CD3E CHN1 CPSF6 CPSF7 DDR1 DNM1 DOCK1 DOK1 DRAP1 DVL1 EEF1G EFHC2 EFNB1 EFNB2 EFS EGFR EIF3H ERBB2 ERBB3 FAM53C FASLG FCRL2 FGFR1 FXR2 FYB1 HNRNPK HOMEZ HOXC4 ILK IRS1 KHDRBS1 KIAA1217 LCP2 LIMS1 LNX1 LRRIQ3 LZTS2 MAGEA6 MASP1 MEOX2 NCKIPSD NPHS1 NR5A1 NTRK2 PAK1 PDGFRB PIK3AP1 PKD1 PKN2 PRR20A PSMD10 PTK2 RASSF7 RBM26 REL SF3B4 SKAP2 SMARCB1 SORBS2 SOS1 SPRY2 SRPK1 SRPK2 SYNPO TCF4 TNR TRIM27 TRIM41 TRIP6 UBC VARS2 VPS37B WAS WASL WBP11 WIPF2 ZBTB7B 11 interacting genes: BCAR1 CRK CYTH2 ELMO1 ELMO2 NCK2 PRKACA RAC1 RHOG TAMALIN WASF2
Entrez ID 8440 1793
HPRD ID 05378 03240
Ensembl ID ENSG00000071051 ENSG00000150760
Uniprot IDs A0A0S2Z4M6 E7ERP6 O43639 A0A2X0U2H5 B2RUU3 Q14185
PDB IDs 1U5S 1WX6 1Z3K 2B86 2CIA 2FRW 2FRY 2JXB 4E6R 3L4C
Enriched GO Terms of Interacting Partners?
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