RECK and TRIM69

Number of citations of the paper that reports this interaction (PubMedID 21516116)
94

Data Source:
BioGRID (two hybrid)

		RECK	TRIM69
Description		reversion inducing cysteine rich protein with kazal motifs	tripartite motif containing 69
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Membrane Anchored Component Of Membrane Wnt Signalosome	Nucleus Cytoplasm Cytosol Nuclear Speck
	Molecular Function	Endopeptidase Inhibitor Activity Serine-type Endopeptidase Inhibitor Activity Protein Binding Metalloendopeptidase Inhibitor Activity Wnt-protein Binding Coreceptor Activity Involved In Canonical Wnt Signaling Pathway	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding
	Biological Process	Vasculature Development Blood Vessel Maturation Sprouting Angiogenesis Embryo Implantation Negative Regulation Of Endopeptidase Activity Extracellular Matrix Organization Negative Regulation Of Cell Migration Embryonic Forelimb Morphogenesis Regulation Of Angiogenesis Canonical Wnt Signaling Pathway Regulation Of Establishment Of Blood-brain Barrier Positive Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Metalloendopeptidase Activity	Protein Polyubiquitination Apoptotic Process
Pathways		Post-translational modification: synthesis of GPI-anchored proteins	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Bipolar disorder (inflammation and infection response interaction) ( 25781172) IgG glycosylation ( 23382691)	Estimated glomerular filtration rate in non-diabetics ( 31451708)
Interacting Genes		15 interacting genes: CEP44 CTH KEAP1 KRT40 MEOX2 MMP9 MTNR1B NOTCH2NLA REL SIGMAR1 TCF4 TEKT4 TRIM39 TRIM69 USHBP1	28 interacting genes: APP ASNS ATP5MC1 DVL1 FAM110A FKBP1B HAUS1 HGS IYD KRT17 LARP1B MAGEA4 NEK8 PML PPP1R18 RECK RSPH14 SF1 SF3A3 SKIL SYNE4 TRIM44 UBE2D1 UBE2D3 UBE2E1 UBE2H UBE2N ZNF483
Entrez ID		8434	140691
HPRD ID		05567	11518
Ensembl ID		ENSG00000122707	ENSG00000185880
Uniprot IDs		A8K9D8 O95980 Q6P9E2	H0YL66 Q86WT6
PDB IDs			4NQJ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?