TRIM69 and HAUS1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TRIM69	HAUS1
Description		tripartite motif containing 69	HAUS augmin like complex subunit 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Nuclear Speck	Spindle Pole Centrosome Cytosol Microtubule HAUS Complex
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding	Molecular_function Protein Binding
	Biological Process	Protein Polyubiquitination Apoptotic Process	G2/M Transition Of Mitotic Cell Cycle Centrosome Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Spindle Assembly Cell Division Ciliary Basal Body-plasma Membrane Docking
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Estimated glomerular filtration rate in non-diabetics ( 31451708)
Interacting Genes		28 interacting genes: APP ASNS ATP5MC1 DVL1 FAM110A FKBP1B HAUS1 HGS IYD KRT17 LARP1B MAGEA4 NEK8 PML PPP1R18 RECK RSPH14 SF1 SF3A3 SKIL SYNE4 TRIM44 UBE2D1 UBE2D3 UBE2E1 UBE2H UBE2N ZNF483	68 interacting genes: AK8 ARFIP2 BLOC1S6 C3orf62 CAGE1 CBY2 CCDC114 CCDC136 CCDC57 CCHCR1 CDR2 CEP170P1 CEP44 CEP55 CEP57L1 CEP63 CEP70 DCTN2 DMD DTNBP1 FGFR1OP2 GOLGA2 HOOK2 IFIT3 IFT20 INCA1 KDM1A KIFC3 KRT15 KRT18 KRT19 KRT31 KRT38 KRT40 KXD1 LDOC1 LURAP1 MAD1L1 MAGEA6 MCM10 MCM3 MED4 MED7 MIPOL1 MTUS2 NDC80 NECAB2 NINL NUP54 NUP62 PDE4DIP PIBF1 SPAG5 STX11 SYCE1 SYCE3 TFIP11 TFPT TRAF1 TRIM23 TRIM27 TRIM54 TRIM69 TSG101 USHBP1 VPS52 WASHC3 ZNF471
Entrez ID		140691	115106
HPRD ID		11518	16385
Ensembl ID		ENSG00000185880	ENSG00000152240
Uniprot IDs		H0YL66 Q86WT6	Q96CS2
PDB IDs		4NQJ
Enriched GO Terms of Interacting Partners?
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