AKT1S1 and TCEA2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		AKT1S1	TCEA2
Description		AKT1 substrate 1	transcription elongation factor A2
Image
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol TORC1 Complex	Transcription Elongation Factor Complex
	Molecular Function	Protein Binding	DNA Binding Protein Binding Zinc Ion Binding
	Biological Process	Negative Regulation Of Protein Kinase Activity Negative Regulation Of TOR Signaling Regulation Of Apoptotic Process Regulation Of Neuron Apoptotic Process Negative Regulation Of Cell Size Neurotrophin TRK Receptor Signaling Pathway Regulation Of Cellular Response To Heat	DNA-templated Transcription, Elongation Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Transcription By RNA Polymerase II
Pathways		mTOR signalling mTORC1-mediated signalling AKT phosphorylates targets in the cytosol HSF1-dependent transactivation Constitutive Signaling by AKT1 E17K in Cancer
Drugs
Diseases
GWAS			Adventurousness ( 30643258) Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Pulse pressure ( 27841878 30578418) Serum thyroid-stimulating hormone levels ( 25436638) Systolic blood pressure ( 27841878) Triglyceride levels ( 29083408) Type 2 diabetes (adjusted for BMI) ( 30297969)
Interacting Genes		9 interacting genes: AKT1 AKT2 EIF6 FZR1 MTOR RPS6KA5 TCEA2 YWHAG YWHAQ	50 interacting genes: ADAMTSL4 AKT1S1 ALAS1 APP BRCA1 CAMKV CCDC136 CCSER2 CDK11B CENPT CEP44 DAB1 DCAF10 DHRS2 DNAJB9 EAF2 EXOSC8 FAM9B FBF1 GOLGA2 GPKOW GRIPAP1 GTF2B KIAA1958 KRT40 KRTAP10-7 KRTAP5-9 KXD1 LMNA LRRK2 LZTS2 MAGEA11 MARK3 MCM2 MEOX2 MID2 MKRN3 RPA1 SH3GL2 TAX1BP1 TAX1BP3 TCF4 TFCP2 THAP1 TNIP1 TRAF2 TRIM27 TRIM54 TSGA10 WDR47
Entrez ID		84335	6919
HPRD ID		12441	16069
Ensembl ID		ENSG00000204673	ENSG00000171703
Uniprot IDs		A0A024QZF6 Q96B36	Q15560 Q6IB64
PDB IDs		5WBL 5WBU 5WBY 6SB0	2LW4
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?