ZCCHC7 and PHC1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		ZCCHC7	PHC1
Description		zinc finger CCHC-type containing 7	polyhomeotic homolog 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleolus Cytosol	Nucleus Nucleoplasm PcG Protein Complex PRC1 Complex
	Molecular Function	RNA Binding Protein Binding Zinc Ion Binding	DNA Binding Protein Binding Zinc Ion Binding
	Biological Process		Multicellular Organism Development Histone Ubiquitination Negative Regulation Of G0 To G1 Transition
Pathways			Oxidative Stress Induced Senescence SUMOylation of DNA damage response and repair proteins SUMOylation of transcription cofactors SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA methylation proteins RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Regulation of PTEN gene transcription Regulation of PTEN gene transcription Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Bipolar disorder ( 31043756) Bitter beverage consumption ( 31046077) Chronotype ( 30696823) HIV-1 susceptibility ( 25786224) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Metabolite risk score for predicting weight gain ( 31560688) Morning person ( 30696823) Severe bacterial meningitis ( 31092817)	Antisaccade task score ( 31596458) Cholesterol, total ( 24097068) Height ( 31562340) Prepulse inhibition of the startle response ( 31596458) Small cell lung carcinoma ( 28604730) Total cholesterol levels ( 28334899)
Interacting Genes		7 interacting genes: CARD9 CREBBP PHC1 SNIP1 SUMO1 SUMO2 UBE2I	17 interacting genes: BMI1 GMNN HSPA8 PHC2 PIAS2 PPP1CA PPP1CC RING1 RNF2 SCMH1 SFMBT1 SIAH1 SP100 SUMO1 SUMO1P1 UBE2I ZCCHC7
Entrez ID		84186	1911
HPRD ID		15703	16009
Ensembl ID		ENSG00000147905	ENSG00000111752
Uniprot IDs		Q05DN1 Q8N3Z6	P78364 Q6GMQ3 Q6N083
PDB IDs			2L8E
Enriched GO Terms of Interacting Partners?
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