PHC1

Description		polyhomeotic homolog 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm PcG Protein Complex PRC1 Complex
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding
	Biological Process	Multicellular Organism Development Histone Ubiquitination Negative Regulation Of G0 To G1 Transition
Pathways		Oxidative Stress Induced Senescence SUMOylation of DNA damage response and repair proteins SUMOylation of transcription cofactors SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA methylation proteins RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Regulation of PTEN gene transcription Regulation of PTEN gene transcription Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS		Antisaccade task score ( 31596458) Cholesterol, total ( 24097068) Height ( 31562340) Prepulse inhibition of the startle response ( 31596458) Small cell lung carcinoma ( 28604730) Total cholesterol levels ( 28334899)
Interacting Genes		17 interacting genes: BMI1 GMNN HSPA8 PHC2 PIAS2 PPP1CA PPP1CC RING1 RNF2 SCMH1 SFMBT1 SIAH1 SP100 SUMO1 SUMO1P1 UBE2I ZCCHC7
Entrez ID		1911
HPRD ID		16009
Ensembl ID		ENSG00000111752
Uniprot IDs		P78364 Q6GMQ3 Q6N083
PDB IDs		2L8E
Enriched GO Terms of Interacting Partners?
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