EEA1 and STX12

Number of citations of the paper that reports this interaction (PubMedID 10458612)
161

Data Source:
HPRD (in vitro)

		EEA1	STX12
Description		early endosome antigen 1	syntaxin 12
Image
GO Annotations	Cellular Component	Cytoplasm Early Endosome Cytosol Serine-pyruvate Aminotransferase Complex Membrane Extrinsic Component Of Plasma Membrane Early Endosome Membrane Axonal Spine Recycling Endosome Extracellular Exosome	Golgi Membrane Phagophore Assembly Site Synaptic Vesicle Endomembrane System Integral Component Of Membrane Integral Component Of Synaptic Vesicle Membrane BLOC-1 Complex SNARE Complex Early Endosome Membrane Vesicle Membrane Raft Phagocytic Vesicle Recycling Endosome Membrane Postsynaptic Recycling Endosome
	Molecular Function	Nucleic Acid Binding Protein Binding Calmodulin Binding 1-phosphatidylinositol Binding Zinc Ion Binding GTP-dependent Protein Binding Protein Homodimerization Activity	SNARE Binding SNAP Receptor Activity Protein Binding
	Biological Process	Endocytosis Vesicle Fusion Synaptic Vesicle To Endosome Fusion Viral RNA Genome Replication Early Endosome To Late Endosome Transport	Autophagosome Assembly Intracellular Protein Transport Vesicle Fusion Cholesterol Efflux Vesicle Docking Protein Stabilization
Pathways		Toll Like Receptor 9 (TLR9) Cascade
Drugs		Inositol 1,3-Bisphosphate
Diseases
GWAS		Diastolic blood pressure x smoking status (current vs non-current) interaction (1df test) ( 29455858) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Sensorimotor dexterity ( 31596458) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Western dietary pattern ( 28644415)
Interacting Genes		13 interacting genes: IGF1R MAPK14 RAB22A RAB31 RAB5A RAB5B RAB5C RRAD STX12 STX6 TOM1 USO1 ZFYVE16	12 interacting genes: BLOC1S6 DNAJC5 DTX2 EEA1 EPB42 HOMER1 LMNA NAPA NSG1 SNAP23 SNAP25 SNAP29
Entrez ID		8411	23673
HPRD ID		05460	06059
Ensembl ID		ENSG00000102189	ENSG00000117758
Uniprot IDs		Q15075	Q86Y82
PDB IDs		1HYI 1HYJ 1JOC 3MJH	2DNX
Enriched GO Terms of Interacting Partners?
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