CASP8 and CDH13

  • Number of citations of the paper that reports this interaction (PubMedID 25640309)
  • 5
  • Data Source:
  • BioGRID (two hybrid)

CASP8

CDH13

Description caspase 8 cadherin 13
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adiponectin levels ( 20876611 22479202 22065538 20887962 21771975 24105470)
  • Adolescent idiopathic scoliosis ( 31417091 30395268)
  • Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+doxorubicin+/-5FU) ( 24025145)
  • Adverse response to chemotherapy in breast cancer (alopecia) (paclitaxel) ( 24025145)
  • Alcohol consumption (heavy vs. light/non-drinkers) ( 27911795)
  • Attention deficit hyperactivity disorder ( 18839057)
  • Bipolar disorder ( 31043756)
  • Blood pressure ( 17903302)
  • Bortezomib-induced peripheral neuropathy in multiple myeloma ( 28317148)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Coronary artery disease ( 29212778 30104761 28714974)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • Crohn's disease ( 28067908)
  • D-dimer levels ( 21502573)
  • Daytime sleep phenotypes ( 27126917)
  • Dental caries (decayed, missing and filled teeth) ( 31533690)
  • Depression (quantitative trait) ( 20800221)
  • Diastolic blood pressure ( 27841878 31170924 30578418)
  • Dimensional psychopathology (Arousal) ( 29496196)
  • Dimensional psychopathology (Negative) ( 29496196)
  • Erectile dysfunction ( 30583798)
  • Feeling hurt ( 29500382)
  • Feeling tense ( 29500382)
  • Gait speed in old age ( 28077804)
  • General risk tolerance (MTAG) ( 30643258)
  • Glucose homeostasis traits ( 25524916)
  • Height ( 20189936)
  • Hippocampal volume ( 31530798)
  • Homeostasis model assessment of beta-cell function (dietary factor interaction) ( 24204828)
  • Hypertension ( 19304780)
  • Hypothyroidism ( 27182965)
  • IgE levels in asthmatics (D.f. specific) ( 23967269)
  • Maximal oxygen uptake response ( 25729143)
  • Night sleep phenotypes ( 27126917)
  • Periodontitis (Mean PAL) ( 24024966)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
  • Precuneus cortex volume ( 31530798)
  • Pulse pressure ( 28135244 27841878 28739976 30578418)
  • Rapid automised naming of digits ( 30741946)
  • Refractive astigmatism ( 30306274)
  • Response to amphetamines ( 22952603)
  • Response to antipsychotic treatment ( 20195266)
  • Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814)
  • Response to fenofibrate (adiponectin levels) ( 23149075)
  • Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872)
  • Schizophrenia ( 23358160)
  • Seasonality and depression ( 30217971)
  • Short-term memory (digit-span task) ( 30741946)
Interacting Genes 127 interacting genes: AGR3 ANGPTL4 APAF1 APP AR ATAD2 ATG4D ATP1A3 BAP1 BCAP31 BCL2 BCL2L1 BCL2L10 BEX1 BFAR BID BIRC6 BLID CASC3 CASP1 CASP10 CASP14 CASP2 CASP3 CASP4 CASP6 CASP7 CASP8AP2 CASP9 CDH1 CDH13 CDK11B CDKN1B CFLAR CHD3 CHUK CNBP COPS6 CRADD CTNNB1 DEDD DEDD2 EDA2R EIF2AK2 EPSTI1 ERRFI1 FADD FAF1 FAS FYN GLCE GMEB1 GREB1 GRIA1 GZMB HBP1 HDAC7 HECTD3 HIP1 IKBKB IKBKG IL13RA2 IL24 ILK KLK5 KLK9 KRT18 LYPD3 MAP1LC3B MAP3K14 MAP4K4 MAPK1 MAPK3 MAPT NOD1 NOL3 NR1H4 NSD3 PARK7 PARP1 PARP2 PCYT1A PDIA6 PEA15 PIAS1 PICALM PIK3C3 PLA2G4B PLEC PLIN4 PRDM14 PRDX6 PRKCI PRKCZ PRKN PRSS50 PSEN1 PSEN2 PSMC3IP QDPR RALBP1 RB1 RIPK1 RIPK2 RYBP S100A14 SCGB2A2 SERPINB5 SNRPD3 SOX2 SRF ST14 STK24 SUMO1 TFCP2 TNFRSF10A TNFRSF10B TOPORS TRAF1 TRAF2 TRAF6 UBC UMPS USO1 VIM VPS45 YBX1 10 interacting genes: ADIPOQ AURKA CASP8 CCND1 CHEK2 HMMR MAPK6 MTNR1B PTPN1 RAD51
Entrez ID 841 1012
HPRD ID 03459 03219
Ensembl ID ENSG00000064012 ENSG00000140945
Uniprot IDs A0A024R3Z8 Q14790 B7Z3H7 B7Z9B1 P55290
PDB IDs 1F9E 1I4E 1QDU 1QTN 2C2Z 2FUN 2K7Z 2Y1L 3H11 3KJN 3KJQ 4JJ7 4PRZ 4PS1 4ZBW 5H31 5H33 5JQE 5L08 6AGW 2V37
Enriched GO Terms of Interacting Partners?
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