CASP8 and ANGPTL4

  • Number of citations of the paper that reports this interaction (PubMedID 25640309)
  • 5
  • Data Source:
  • BioGRID (two hybrid)

CASP8

ANGPTL4

Description caspase 8 angiopoietin like 4
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Coronary artery disease ( 29212778)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • HDL cholesterol ( 24097068 28270201 24507774 19060906 30275531 25961943 20686565)
  • HDL cholesterol levels ( 28334899 30698716)
  • HDL cholesterol levels in current drinkers ( 30698716)
  • HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • HDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535)
  • HDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535)
  • Metabolic syndrome ( 31589552)
  • Metabolite levels (lipoprotein measures) ( 27005778)
  • Phospholipid levels in large HDL ( 29084231)
  • Total cholesterol levels in HDL ( 29084231)
  • Total triglycerides levels ( 29084231)
  • Triglyceride levels ( 30698716)
  • Triglyceride levels in current drinkers ( 30698716)
  • Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Triglycerides ( 24507774 30275531 25961943 27036123)
  • Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
Interacting Genes 127 interacting genes: AGR3 ANGPTL4 APAF1 APP AR ATAD2 ATG4D ATP1A3 BAP1 BCAP31 BCL2 BCL2L1 BCL2L10 BEX1 BFAR BID BIRC6 BLID CASC3 CASP1 CASP10 CASP14 CASP2 CASP3 CASP4 CASP6 CASP7 CASP8AP2 CASP9 CDH1 CDH13 CDK11B CDKN1B CFLAR CHD3 CHUK CNBP COPS6 CRADD CTNNB1 DEDD DEDD2 EDA2R EIF2AK2 EPSTI1 ERRFI1 FADD FAF1 FAS FYN GLCE GMEB1 GREB1 GRIA1 GZMB HBP1 HDAC7 HECTD3 HIP1 IKBKB IKBKG IL13RA2 IL24 ILK KLK5 KLK9 KRT18 LYPD3 MAP1LC3B MAP3K14 MAP4K4 MAPK1 MAPK3 MAPT NOD1 NOL3 NR1H4 NSD3 PARK7 PARP1 PARP2 PCYT1A PDIA6 PEA15 PIAS1 PICALM PIK3C3 PLA2G4B PLEC PLIN4 PRDM14 PRDX6 PRKCI PRKCZ PRKN PRSS50 PSEN1 PSEN2 PSMC3IP QDPR RALBP1 RB1 RIPK1 RIPK2 RYBP S100A14 SCGB2A2 SERPINB5 SNRPD3 SOX2 SRF ST14 STK24 SUMO1 TFCP2 TNFRSF10A TNFRSF10B TOPORS TRAF1 TRAF2 TRAF6 UBC UMPS USO1 VIM VPS45 YBX1 9 interacting genes: AURKA BRMS1 CASP8 CDKN2A CDKN2C ESR1 FBXW7 FGFR4 TGFB1
Entrez ID 841 51129
HPRD ID 03459 16173
Ensembl ID ENSG00000064012 ENSG00000167772
Uniprot IDs A0A024R3Z8 Q14790 Q9BY76
PDB IDs 1F9E 1I4E 1QDU 1QTN 2C2Z 2FUN 2K7Z 2Y1L 3H11 3KJN 3KJQ 4JJ7 4PRZ 4PS1 4ZBW 5H31 5H33 5JQE 5L08 6AGW 6EUB 6U0A 6U1U 6U73
Enriched GO Terms of Interacting Partners?
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