CDH13 and MAPK6

  • Number of citations of the paper that reports this interaction (PubMedID 21900206)
  • 114
  • Data Source:
  • BioGRID (two hybrid)

CDH13

MAPK6

Description cadherin 13 mitogen-activated protein kinase 6
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adiponectin levels ( 20876611 22479202 22065538 20887962 21771975 24105470)
  • Adolescent idiopathic scoliosis ( 31417091 30395268)
  • Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+doxorubicin+/-5FU) ( 24025145)
  • Adverse response to chemotherapy in breast cancer (alopecia) (paclitaxel) ( 24025145)
  • Alcohol consumption (heavy vs. light/non-drinkers) ( 27911795)
  • Attention deficit hyperactivity disorder ( 18839057)
  • Bipolar disorder ( 31043756)
  • Blood pressure ( 17903302)
  • Bortezomib-induced peripheral neuropathy in multiple myeloma ( 28317148)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Coronary artery disease ( 29212778 30104761 28714974)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • Crohn's disease ( 28067908)
  • D-dimer levels ( 21502573)
  • Daytime sleep phenotypes ( 27126917)
  • Dental caries (decayed, missing and filled teeth) ( 31533690)
  • Depression (quantitative trait) ( 20800221)
  • Diastolic blood pressure ( 27841878 31170924 30578418)
  • Dimensional psychopathology (Arousal) ( 29496196)
  • Dimensional psychopathology (Negative) ( 29496196)
  • Erectile dysfunction ( 30583798)
  • Feeling hurt ( 29500382)
  • Feeling tense ( 29500382)
  • Gait speed in old age ( 28077804)
  • General risk tolerance (MTAG) ( 30643258)
  • Glucose homeostasis traits ( 25524916)
  • Height ( 20189936)
  • Hippocampal volume ( 31530798)
  • Homeostasis model assessment of beta-cell function (dietary factor interaction) ( 24204828)
  • Hypertension ( 19304780)
  • Hypothyroidism ( 27182965)
  • IgE levels in asthmatics (D.f. specific) ( 23967269)
  • Maximal oxygen uptake response ( 25729143)
  • Night sleep phenotypes ( 27126917)
  • Periodontitis (Mean PAL) ( 24024966)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
  • Precuneus cortex volume ( 31530798)
  • Pulse pressure ( 28135244 27841878 28739976 30578418)
  • Rapid automised naming of digits ( 30741946)
  • Refractive astigmatism ( 30306274)
  • Response to amphetamines ( 22952603)
  • Response to antipsychotic treatment ( 20195266)
  • Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814)
  • Response to fenofibrate (adiponectin levels) ( 23149075)
  • Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872)
  • Schizophrenia ( 23358160)
  • Seasonality and depression ( 30217971)
  • Short-term memory (digit-span task) ( 30741946)
  • Serum uric acid levels in response to allopurinol in gout ( 25676789)
Interacting Genes 10 interacting genes: ADIPOQ AURKA CASP8 CCND1 CHEK2 HMMR MAPK6 MTNR1B PTPN1 RAD51 166 interacting genes: ACTG1 ACTR1B AMPH ANAPC5 ANK3 APBA2 ARHGDIA ARPC3 ATG9A ATP5PF BAG6 BARX1 BBS10 CA1 CA12 CALR CASP6 CCND3 CCT3 CDH13 CERS1 CFAP298 CFL1 CNTN1 CNTRL COPS6 CSE1L CYRIB CYTH2 DBN1 DCTN2 DDOST DDR1 DGKZ DKC1 DNAJC28 DPPA4 DST EDF1 EEF1A2 EIF1 EIF3C EIF4A1 ELOF1 EMD FBXL16 FOXO3 FXYD3 GALNT7 GATA1 GLRX3 GORASP1 GPX1 HACL1 HAUS2 HDAC11 HIP1 HNRNPA0 HNRNPD HNRNPH3 HSP90AB1 HSP90B1 HSPD1 IDH3B INS ITGB3BP ITSN1 JUNB KDSR KLC1 KNSTRN LPXN MAP3K12 MAP3K7 MAPKAPK5 MASP1 MBIP MBOAT7 MCM3 MDK METTL17 METTL2A MGAT1 MIPEP MOK MON1A MTG2 MYBL2 MYOZ3 MZB1 NAT9 NAXE NDUFS6 NECTIN2 NELFB NOL4 NRXN2 NUDT5 OSTF1 PDCD6IP PDLIM1 PHACTR3 PHC2 PHGDH PIH1D1 PLEKHM1 PLSCR1 PPBP PPP1R7 PPP2R1A PRKAB1 PRKAR1A PRKCB PRPF38A PSAT1 PSIP1 PTPMT1 RAB2A RAB31 RACK1 RANBP9 RAP1GAP RARA RBL1 RGS19 RPL10 RRP7A SEPTIN3 SEPTIN5 SERPINA4 SHC1 SLC20A1 SLC41A3 SMAD6 SMS SNAPC4 SNW1 SOCS3 SPG7 SPRR2D SPTAN1 SRSF5 STX7 TCF12 TDP2 THAP4 TPI1 TTK TUBA1A UBA52 UBE2L3 URB1 USP20 VPS26C WDR26 WDR34 WFS1 WWC1 XPO1 ZNF133 ZNF205 ZNF331 ZNF579 ZNF600 ZNF671 ZNF775
Entrez ID 1012 5597
HPRD ID 03219 04213
Ensembl ID ENSG00000140945 ENSG00000069956
Uniprot IDs B7Z3H7 B7Z9B1 P55290 Q16659
PDB IDs 2V37 2I6L
Enriched GO Terms of Interacting Partners?
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