UXT and PAK5

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		UXT	PAK5
Description		ubiquitously expressed prefoldin like chaperone	p21 (RAC1) activated kinase 5
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Spindle Pole Gamma-tubulin Complex Nucleus Nucleoplasm Cytoplasm Centrosome Cytoskeleton	Nucleoplasm Cytoplasm Mitochondrion Synapse
	Molecular Function	Chromatin Binding Transcription Coregulator Activity Transcription Corepressor Activity Protein Binding Microtubule Binding Beta-tubulin Binding Actin Filament Binding	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Microtubule Cytoskeleton Organization Regulation Of Transcription By RNA Polymerase II Apoptotic Process Centrosome Cycle Mitochondrion Transport Along Microtubule Negative Regulation Of G0 To G1 Transition	Regulation Of Cell Growth Apoptotic Process Cytoskeleton Organization Signal Transduction Regulation Of Mitotic Cell Cycle Learning Memory Locomotory Behavior Cell Proliferation Cell Migration Signal Transduction By Protein Phosphorylation Stress-activated Protein Kinase Signaling Cascade Activation Of Protein Kinase Activity Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways		Transcriptional Regulation by E2F6	Activation of RAC1
Drugs
Diseases
GWAS			Atopy ( 28927820) Plasma factor V levels in venous thrombosis (conditioned on rs6027) ( 31271701)
Interacting Genes		22 interacting genes: APP AR CECR2 FBXO7 GLE1 KRT31 KRT40 KRTAP10-7 KRTAP10-8 LRPPRC LSM1 MACROD1 MCPH1 NOTCH2NLA PAK5 RCAN1 RUNX1 SIAH1 SVIL TRIM55 TRIM63 VHL	21 interacting genes: ARMC7 ATPAF2 BAD CARD9 CCNG1 CDC42 CRBN EMD EXOSC1 FHL3 GCC1 INKA1 LENG1 LZTS2 PDLIM7 PRPF31 PSMF1 RAC1 SORBS3 TUBGCP4 UXT
Entrez ID		8409	57144
HPRD ID		02209	06423
Ensembl ID		ENSG00000126756	ENSG00000101349
Uniprot IDs		Q9UBK9	B0AZM9 Q9P286
PDB IDs			2F57
Enriched GO Terms of Interacting Partners?
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