UXT and LSM1

Number of citations of the paper that reports this interaction (PubMedID 15231747)
56

Data Source:
HPRD (two hybrid)

		UXT	LSM1
Description		ubiquitously expressed prefoldin like chaperone	LSM1 homolog, mRNA degradation associated
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Spindle Pole Gamma-tubulin Complex Nucleus Nucleoplasm Cytoplasm Centrosome Cytoskeleton	P-body Nucleus Cytoplasm Cytosol Axon Dendrite Neuronal Cell Body Messenger Ribonucleoprotein Complex Lsm1-7-Pat1 Complex
	Molecular Function	Chromatin Binding Transcription Coregulator Activity Transcription Corepressor Activity Protein Binding Microtubule Binding Beta-tubulin Binding Actin Filament Binding	RNA Cap Binding RNA Binding MRNA Binding Protein Binding Pre-mRNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Microtubule Cytoskeleton Organization Regulation Of Transcription By RNA Polymerase II Apoptotic Process Centrosome Cycle Mitochondrion Transport Along Microtubule Negative Regulation Of G0 To G1 Transition	Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA RNA Splicing, Via Transesterification Reactions MRNA Processing RNA Splicing RNA Metabolic Process Stem Cell Population Maintenance Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Negative Regulation Of Neuron Differentiation Histone MRNA Catabolic Process
Pathways		Transcriptional Regulation by E2F6	mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease
Drugs
Diseases
GWAS			Autism spectrum disorder or schizophrenia ( 28540026) Schizophrenia ( 28991256 22037555 29483656)
Interacting Genes		22 interacting genes: APP AR CECR2 FBXO7 GLE1 KRT31 KRT40 KRTAP10-7 KRTAP10-8 LRPPRC LSM1 MACROD1 MCPH1 NOTCH2NLA PAK5 RCAN1 RUNX1 SIAH1 SVIL TRIM55 TRIM63 VHL	27 interacting genes: CLIC1 EXOSC6 EXOSC8 GLUD1 GOLGA7 GRHPR HSP90AA1 LSM2 LSM3 LSM4 LSM5 LSM6 LSM7 MPDU1 N4BP1 NARS1 NDUFAF3 PSMB5 PSMB8 PTPRC RRP1B SMN1 TFCP2 TMEM214 UPF2 UXT VPS11
Entrez ID		8409	27257
HPRD ID		02209	06281
Ensembl ID		ENSG00000126756	ENSG00000175324
Uniprot IDs		Q9UBK9	A0A0S2Z590 O15116
PDB IDs
Enriched GO Terms of Interacting Partners?
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