LSM1 and N4BP1

Number of citations of the paper that reports this interaction (PubMedID 15231747)
56

Data Source:
BioGRID (two hybrid)

		LSM1	N4BP1
Description		LSM1 homolog, mRNA degradation associated	NEDD4 binding protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	P-body Nucleus Cytoplasm Cytosol Axon Dendrite Neuronal Cell Body Messenger Ribonucleoprotein Complex Lsm1-7-Pat1 Complex	Nucleolus PML Body
	Molecular Function	RNA Cap Binding RNA Binding MRNA Binding Protein Binding Pre-mRNA Binding	Protein Binding
	Biological Process	Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA RNA Splicing, Via Transesterification Reactions MRNA Processing RNA Splicing RNA Metabolic Process Stem Cell Population Maintenance Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Negative Regulation Of Neuron Differentiation Histone MRNA Catabolic Process	Negative Regulation Of Protein Ubiquitination Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cellular Response To UV
Pathways		mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Schizophrenia ( 28991256 22037555 29483656)	Eosinophil counts ( 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252) Neutrophil percentage of granulocytes ( 27863252) Social autistic-like traits ( 24133439) Sum eosinophil basophil counts ( 27863252)
Interacting Genes		27 interacting genes: CLIC1 EXOSC6 EXOSC8 GLUD1 GOLGA7 GRHPR HSP90AA1 LSM2 LSM3 LSM4 LSM5 LSM6 LSM7 MPDU1 N4BP1 NARS1 NDUFAF3 PSMB5 PSMB8 PTPRC RRP1B SMN1 TFCP2 TMEM214 UPF2 UXT VPS11	6 interacting genes: AZI2 CDK6 ITCH LSM1 NEDD8 UBC
Entrez ID		27257	9683
HPRD ID		06281
Ensembl ID		ENSG00000175324	ENSG00000102921
Uniprot IDs		A0A0S2Z590 O15116	O75113
PDB IDs
Enriched GO Terms of Interacting Partners?
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