DOCK8 and MRPL38

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		DOCK8	MRPL38
Description		dedicator of cytokinesis 8	mitochondrial ribosomal protein L38
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Membrane Leading Edge Membrane Lamellipodium Membrane	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Large Ribosomal Subunit
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding	Protein Binding
	Biological Process	Immunological Synapse Formation Small GTPase Mediated Signal Transduction Blood Coagulation Dendritic Cell Migration Positive Regulation Of GTPase Activity Memory T Cell Proliferation Negative Regulation Of T Cell Apoptotic Process Positive Regulation Of Establishment Of T Cell Polarity Cellular Response To Chemokine Positive Regulation Of T Cell Migration	Mitochondrial Translational Elongation Mitochondrial Translational Termination
Pathways		Factors involved in megakaryocyte development and platelet production	Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination
Drugs
Diseases		Non-syndromic autosomal dominant mental retardation
GWAS		Blond vs. brown/black hair color ( 30531825) Granulocyte count ( 27863252) Granulocyte percentage of myeloid white cells ( 27863252) Heel bone mineral density ( 30598549) Mean platelet volume ( 22139419 27863252) Myeloid white cell count ( 27863252) Neutrophil count ( 27863252) Nevus count ( 30429480) Nevus count or cutaneous melanoma ( 30429480) Obesity-related traits ( 23251661) Platelet count ( 27863252) Platelet distribution width ( 27863252) Post bronchodilator FEV1 ( 26634245) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) White blood cell count ( 27863252)
Interacting Genes		24 interacting genes: BYSL CARHSP1 CDC42 CHMP2A DGCR6 EXOSC5 FAM124A FAM161A FANCL FBXL12 HBZ KRT40 MED30 MEOX2 MRPL38 MTG1 PIMREG RAC1 RHOJ RHOQ RTP5 SMAD2 ZFC3H1 ZNF581	5 interacting genes: CSNK2A1 DOCK8 ERG28 HSPB3 PRIM1
Entrez ID		81704	64978
HPRD ID		10920	14758
Ensembl ID		ENSG00000107099	ENSG00000204316
Uniprot IDs		E2J6M5 E2J6M6 Q8NF50	Q96DV4
PDB IDs			3J7Y 3J9M 5OOL 5OOM 6NU2 6NU3
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?