ZBP1 and PALD1

Number of citations of the paper that reports this interaction (PubMedID 21903422)
114

		ZBP1	PALD1
Description		Z-DNA binding protein 1	phosphatase domain containing paladin 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Cytoplasm Cytosol
	Molecular Function	DNA Binding Left-handed Z-DNA Binding Protein Binding	Protein Tyrosine Phosphatase Activity Protein Binding
	Biological Process	Biological_process Regulation Of Type I Interferon Production Positive Regulation Of Type I Interferon Production Innate Immune Response Positive Regulation Of Type I Interferon-mediated Signaling Pathway	Peptidyl-tyrosine Dephosphorylation
Pathways		ZBP1(DAI) mediated induction of type I IFNs IRF3 mediated activation of type 1 IFN IRF3 mediated activation of type 1 IFN RIP-mediated NFkB activation via ZBP1 Regulation of innate immune responses to cytosolic DNA
Drugs
Diseases
GWAS		Hippocampal atrophy ( 19668339) Response to fenofibrate (adiponectin levels) ( 23149075) Verbal declarative memory ( 25648963)	Lymphocyte percentage of white cells ( 27863252) Superior frontal gyrus volume ( 31530798) Type 2 diabetes ( 30130595)
Interacting Genes		8 interacting genes: CTBP1 CTBP2 KLHL12 PALD1 PLXDC2 SIAH1 TRAF3 TRIP6	2 interacting genes: IRF7 ZBP1
Entrez ID		81030	27143
HPRD ID		09484	11419
Ensembl ID		ENSG00000124256	ENSG00000107719
Uniprot IDs		Q9H171	A0A024QZM5 Q9ULE6
PDB IDs		2L4M 2LNB 3EYI 4KA4
Enriched GO Terms of Interacting Partners?
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