EDC3 and DCP1A

Number of citations of the paper that reports this interaction (PubMedID 27107012)
28

Data Source:
BioGRID (two hybrid)

		EDC3	DCP1A
Description		enhancer of mRNA decapping 3	decapping mRNA 1A
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GO Annotations	Cellular Component	P-body Cytosol Membrane Cytoplasmic Ribonucleoprotein Granule	P-body Nucleus Cytoplasm Cytosol Membrane Cytoplasmic Ribonucleoprotein Granule
	Molecular Function	MRNA Binding Protein Binding Identical Protein Binding Phosphodiesterase Decapping Endonuclease Activity	MRNA Binding Protein Binding Enzyme Activator Activity Hydrolase Activity Kinesin Binding Enzyme Regulator Activity Identical Protein Binding
	Biological Process	Deadenylation-independent Decapping Of Nuclear-transcribed MRNA Cytoplasmic MRNA Processing Body Assembly Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay RNA Phosphodiester Bond Hydrolysis, Endonucleolytic	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Deadenylation-independent Decapping Of Nuclear-transcribed MRNA Positive Regulation Of Catalytic Activity Regulation Of MRNA Stability Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Protein Localization To Cytoplasmic Stress Granule
Pathways		mRNA decay by 5' to 3' exoribonuclease	mRNA decay by 5' to 3' exoribonuclease Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Caffeine consumption ( 21490707) Caffeine metabolism (plasma 1,3,7-trimethylxanthine (caffeine) level) ( 27702941) Caffeine metabolism (plasma 1,3-dimethylxanthine (theophylline) level) ( 27702941) Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) to 1,3,7-trimethylxanthine (caffeine) ratio) ( 27702941) Craniofacial microsomia ( 26853712)	Body mass index ( 26426971) Electrocardiographic traits ( 25055868) Erosive tooth wear (severe vs non-severe) ( 29898447) Heart rate ( 23583979) Spontaneous preterm birth (preterm delivery) ( 25599974)
Interacting Genes		9 interacting genes: ANXA10 DCP1A DCP1B DDX6 EFHC2 REEP5 YWHAB YWHAG ZFP36	15 interacting genes: AGO1 AGO2 DCP2 EDC3 FHL2 LSM8 MAPK3 NSMAF PAXIP1 PNRC2 RITA1 SMAD4 TTF2 UPF1 YWHAG
Entrez ID		80153	55802
HPRD ID		07954	06113
Ensembl ID		ENSG00000179151	ENSG00000272886
Uniprot IDs		Q96F86	Q9NPI6
PDB IDs		2VC8 2WAX 2WAY 3D3J 3D3K 6S8S	2WX3 4B6H
Enriched GO Terms of Interacting Partners?
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