CCDC33 and TMCC2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CCDC33	TMCC2
Description		coiled-coil domain containing 33	transmembrane and coiled-coil domain family 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endomembrane System Integral Component Of Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process		Amyloid Precursor Protein Metabolic Process
Pathways
Drugs
Diseases
GWAS		Bacterial meningitis ( 31092817) Craniofacial microsomia ( 26853712) Diastolic blood pressure ( 30224653) Diisocyanate-induced asthma ( 25918132) Obesity-related traits ( 23251661) Systolic blood pressure ( 30578418)	Blood protein levels ( 28240269) High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Immature fraction of reticulocytes ( 27863252) Mean corpuscular hemoglobin ( 29403010 27863252) Mean corpuscular hemoglobin concentration ( 27863252) Mean corpuscular volume ( 27863252) Mean platelet volume ( 22139419 24026423 19820697 27863252) Platelet count ( 22139419) Platelet distribution width ( 27863252) Reticulocyte fraction of red cells ( 27863252)
Interacting Genes		102 interacting genes: ABCF3 ABLIM3 APP ARIH2 ARMC7 ARNT2 BCCIP BLK BLZF1 BYSL CALCOCO2 CCDC102B CCDC85B CCNH CDCA7L CDKN2B CENPP CHCHD3 CRYBA4 DGCR6 DIP2A DVL2 EAF1 EFEMP2 EHMT2 EMC2 EMD FAM124A FAM161A FXR2 GPATCH2L GRN HGS HNRNPF HNRNPK HOOK2 HOXA1 ING5 KANK2 KCTD19 KCTD9 KHDRBS3 KIFC3 KXD1 LDOC1 LMO2 LMO3 MAGED1 MAPK9 MDFI MIPOL1 MLH1 MOS NAB2 NCK2 NDOR1 NECAB2 NEFL NINL OSGIN1 PID1 PIK3R3 PIN1 PLSCR1 PNMA1 PNMA2 POLR1C PPP2R3C PRKAB2 PRPF31 PTGER3 PTK6 RAD51D RAD54B RBMX RHOXF2 RNF6 SCNM1 SMAD3 SMARCB1 SPAG5 SPG21 STK16 STX11 TGFB1 TMCC2 TRAF2 TRIM37 TRIM42 TSC22D4 TSGA10 TTC19 TUFT1 UBQLN4 USHBP1 VPS52 WT1 ZBTB8A ZGPAT ZNF572 ZNF688 ZNRD2	29 interacting genes: AKT1 AMOTL2 APP CCDC33 CDR2 CFAP206 DIP2A DPY30 EIF4E2 FAM161A FAM74A4 FAM90A1 FBF1 HGS HNRNPLL HSPD1 IQUB KAT5 PRPF31 PTOV1 RHOXF2 TLE5 UBA1 WT1-AS ZNF250 ZNF417 ZNF581 ZNF587 ZNF688
Entrez ID		80125	9911
HPRD ID		09959	11040
Ensembl ID		ENSG00000140481	ENSG00000133069
Uniprot IDs		Q8N5R6	A0A0C4DFR1 O75069 Q8IW47
PDB IDs
Enriched GO Terms of Interacting Partners?
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