BTG2 and HOXB9

Number of citations of the paper that reports this interaction (PubMedID 10617598)
41

Data Source:
HPRD (in vitro, two hybrid)

		BTG2	HOXB9
Description		BTG anti-proliferation factor 2	homeobox B9
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Extracellular Exosome	Nuclear Chromatin Nucleus Nucleoplasm Mitochondrion RNA Polymerase II Transcription Factor Complex
	Molecular Function	DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II DNA Repair Protein Methylation Cellular Response To DNA Damage Stimulus DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Negative Regulation Of Cell Proliferation Associative Learning Response To Mechanical Stimulus Anterior/posterior Pattern Specification Response To Organic Cyclic Compound Negative Regulation Of Translation Dentate Gyrus Development Central Nervous System Neuron Development Neuron Projection Development Skeletal Muscle Cell Differentiation Response To Peptide Hormone Negative Regulation Of Neuron Apoptotic Process Negative Regulation Of Mitotic Cell Cycle Response To Electrical Stimulus Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Negative Regulation Of Neural Precursor Cell Proliferation	Transcription, DNA-templated Anterior/posterior Pattern Specification Proximal/distal Pattern Formation Mammary Gland Development Positive Regulation Of Transcription By RNA Polymerase II Embryonic Skeletal System Morphogenesis Cell Chemotaxis
Pathways		TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
Drugs
Diseases
GWAS		Immature fraction of reticulocytes ( 27863252) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Red blood cell count ( 27863252) Red cell distribution width ( 27863252 28957414)	Celiac disease ( 24999842)
Interacting Genes		11 interacting genes: CNOT7 CNOT8 HOXB9 HOXC8 PICK1 PRKCA PRMT1 SKP2 SMAD1 SMAD9 SRA1	26 interacting genes: BTG1 BTG2 CALCOCO2 CREBBP EP300 GOLGA2 HOPX ING4 KAT2B KRTAP10-9 KRTAP4-12 KRTAP5-9 LZTS2 MDFI MID2 MYBBP1A PHTF1 PNMA1 RBPMS SAT1 SIRT1 SOX15 SPZ1 TAL1 TRIP6 ZNF408
Entrez ID		7832	3219
HPRD ID		03357	00852
Ensembl ID		ENSG00000159388	ENSG00000170689
Uniprot IDs		P78543	B3KPJ1 P17482
PDB IDs		3DJU 3E9V
Enriched GO Terms of Interacting Partners?
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