BTG2 and HOXC8

Number of citations of the paper that reports this interaction (PubMedID 10617598)
41

Data Source:
HPRD (in vitro)

		BTG2	HOXC8
Description		BTG anti-proliferation factor 2	homeobox C8
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Extracellular Exosome	Nuclear Chromatin Nucleoplasm Microtubule Cytoskeleton
	Molecular Function	DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Sequence-specific DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II DNA Repair Protein Methylation Cellular Response To DNA Damage Stimulus DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Negative Regulation Of Cell Proliferation Associative Learning Response To Mechanical Stimulus Anterior/posterior Pattern Specification Response To Organic Cyclic Compound Negative Regulation Of Translation Dentate Gyrus Development Central Nervous System Neuron Development Neuron Projection Development Skeletal Muscle Cell Differentiation Response To Peptide Hormone Negative Regulation Of Neuron Apoptotic Process Negative Regulation Of Mitotic Cell Cycle Response To Electrical Stimulus Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Negative Regulation Of Neural Precursor Cell Proliferation	Negative Regulation Of Transcription By RNA Polymerase II Anterior/posterior Pattern Specification Neuron Differentiation Skeletal System Morphogenesis
Pathways		TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
Drugs
Diseases
GWAS		Immature fraction of reticulocytes ( 27863252) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Red blood cell count ( 27863252) Red cell distribution width ( 27863252 28957414)	Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		11 interacting genes: CNOT7 CNOT8 HOXB9 HOXC8 PICK1 PRKCA PRMT1 SKP2 SMAD1 SMAD9 SRA1	12 interacting genes: BMPR1A BTG2 DLX2 DLX5 GMNN HOMEZ JUN MSX1 RBPMS SMAD1 SMAD4 SMAD6
Entrez ID		7832	3224
HPRD ID		03357	00856
Ensembl ID		ENSG00000159388	ENSG00000037965
Uniprot IDs		P78543	P31273
PDB IDs		3DJU 3E9V
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?