HOXB9 and BTG2

Number of citations of the paper that reports this interaction (PubMedID 10617598)
41

Data Source:
HPRD (in vitro, two hybrid)

		HOXB9	BTG2
Description		homeobox B9	BTG anti-proliferation factor 2
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Mitochondrion RNA Polymerase II Transcription Factor Complex	Nucleus Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding	DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding
	Biological Process	Transcription, DNA-templated Anterior/posterior Pattern Specification Proximal/distal Pattern Formation Mammary Gland Development Positive Regulation Of Transcription By RNA Polymerase II Embryonic Skeletal System Morphogenesis Cell Chemotaxis	Negative Regulation Of Transcription By RNA Polymerase II DNA Repair Protein Methylation Cellular Response To DNA Damage Stimulus DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Negative Regulation Of Cell Proliferation Associative Learning Response To Mechanical Stimulus Anterior/posterior Pattern Specification Response To Organic Cyclic Compound Negative Regulation Of Translation Dentate Gyrus Development Central Nervous System Neuron Development Neuron Projection Development Skeletal Muscle Cell Differentiation Response To Peptide Hormone Negative Regulation Of Neuron Apoptotic Process Negative Regulation Of Mitotic Cell Cycle Response To Electrical Stimulus Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Negative Regulation Of Neural Precursor Cell Proliferation
Pathways			TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
Drugs
Diseases
GWAS		Celiac disease ( 24999842)	Immature fraction of reticulocytes ( 27863252) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Red blood cell count ( 27863252) Red cell distribution width ( 27863252 28957414)
Interacting Genes		26 interacting genes: BTG1 BTG2 CALCOCO2 CREBBP EP300 GOLGA2 HOPX ING4 KAT2B KRTAP10-9 KRTAP4-12 KRTAP5-9 LZTS2 MDFI MID2 MYBBP1A PHTF1 PNMA1 RBPMS SAT1 SIRT1 SOX15 SPZ1 TAL1 TRIP6 ZNF408	11 interacting genes: CNOT7 CNOT8 HOXB9 HOXC8 PICK1 PRKCA PRMT1 SKP2 SMAD1 SMAD9 SRA1
Entrez ID		3219	7832
HPRD ID		00852	03357
Ensembl ID		ENSG00000170689	ENSG00000159388
Uniprot IDs		B3KPJ1 P17482	P78543
PDB IDs			3DJU 3E9V
Enriched GO Terms of Interacting Partners?
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