ZMYM2 and SFPQ

Number of citations of the paper that reports this interaction (PubMedID 15975576)
11

Data Source:
HPRD (in vivo)

		ZMYM2	SFPQ
Description		zinc finger MYM-type containing 2	splicing factor proline and glutamine rich
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol PML Body	Chromatin Nucleus Nucleoplasm Nuclear Matrix Nuclear Speck Dendrite Cytoplasm Paraspeckles RNA Polymerase II Transcription Factor Complex
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Zinc Ion Binding Ubiquitin Conjugating Enzyme Binding	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Nucleic Acid Binding DNA Binding Chromatin Binding RNA Binding Protein Binding Protein Homodimerization Activity Histone Deacetylase Binding Transcription Regulatory Region DNA Binding E-box Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Biological_process Regulation Of Cell Morphogenesis	Negative Regulation Of Transcription By RNA Polymerase II Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Double-strand Break Repair Via Homologous Recombination Activation Of Innate Immune Response Regulation Of Transcription, DNA-templated MRNA Processing RNA Splicing Regulation Of Circadian Rhythm Negative Regulation Of Circadian Rhythm Innate Immune Response Positive Regulation Of Sister Chromatid Cohesion Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Rhythmic Process Histone H3 Deacetylation Dendritic Transport Of Messenger Ribonucleoprotein Complex Positive Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Pathways		Signaling by cytosolic FGFR1 fusion mutants Signaling by FGFR1 in disease	PTK6 Regulates Proteins Involved in RNA Processing Suppression of apoptosis
Drugs			Copper Artenimol
Diseases
GWAS		Facial emotion recognition (happy faces) ( 28608620) Hand grip strength ( 29691431)	Allergic disease (asthma, hay fever or eczema) ( 29083406) Endometrial cancer ( 21499250) Hip circumference ( 28552196)
Interacting Genes		21 interacting genes: CEBPE CREB1 CREBBP FUS HNRNPA2B1 HNRNPH3 PTBP1 RCOR1 SFPQ SKIL SMAD3 SMAD4 SNIP1 SREBF2 SUMO1 TSC22D2 UBE2A UBE2I UBTF ZBTB3 ZNF512B	29 interacting genes: APBB1 AR CSNK2A1 ERG ESR1 EXOSC5 FHL2 FUS GAS7 H3-4 JPT1 NONO PIN1 PPARG PPP1CA PRPF40A PSPC1 PTBP1 RAC1 SIN3A SMAD5 SNRPA SREK1 TCERG1 TOP1 UBC UBE2I WBP4 ZMYM2
Entrez ID		7750	6421
HPRD ID		03745	07284
Ensembl ID		ENSG00000121741	ENSG00000116560
Uniprot IDs		A0A024RDS3 A8K126 Q9UBW7	A0A384N5Z8 P23246 Q86VG2
PDB IDs			4WII 4WIJ 4WIK 5WPA 6NCQ
Enriched GO Terms of Interacting Partners?
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