SFPQ and ZMYM2

Number of citations of the paper that reports this interaction (PubMedID 15975576)
11

Data Source:
HPRD (in vivo)

		SFPQ	ZMYM2
Description		splicing factor proline and glutamine rich	zinc finger MYM-type containing 2
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Nuclear Matrix Nuclear Speck Dendrite Cytoplasm Paraspeckles RNA Polymerase II Transcription Factor Complex	Nucleus Cytosol PML Body
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Nucleic Acid Binding DNA Binding Chromatin Binding RNA Binding Protein Binding Protein Homodimerization Activity Histone Deacetylase Binding Transcription Regulatory Region DNA Binding E-box Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Zinc Ion Binding Ubiquitin Conjugating Enzyme Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Double-strand Break Repair Via Homologous Recombination Activation Of Innate Immune Response Regulation Of Transcription, DNA-templated MRNA Processing RNA Splicing Regulation Of Circadian Rhythm Negative Regulation Of Circadian Rhythm Innate Immune Response Positive Regulation Of Sister Chromatid Cohesion Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Rhythmic Process Histone H3 Deacetylation Dendritic Transport Of Messenger Ribonucleoprotein Complex Positive Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway	Regulation Of Transcription By RNA Polymerase II Biological_process Regulation Of Cell Morphogenesis
Pathways		PTK6 Regulates Proteins Involved in RNA Processing Suppression of apoptosis	Signaling by cytosolic FGFR1 fusion mutants Signaling by FGFR1 in disease
Drugs		Copper Artenimol
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Endometrial cancer ( 21499250) Hip circumference ( 28552196)	Facial emotion recognition (happy faces) ( 28608620) Hand grip strength ( 29691431)
Interacting Genes		29 interacting genes: APBB1 AR CSNK2A1 ERG ESR1 EXOSC5 FHL2 FUS GAS7 H3-4 JPT1 NONO PIN1 PPARG PPP1CA PRPF40A PSPC1 PTBP1 RAC1 SIN3A SMAD5 SNRPA SREK1 TCERG1 TOP1 UBC UBE2I WBP4 ZMYM2	21 interacting genes: CEBPE CREB1 CREBBP FUS HNRNPA2B1 HNRNPH3 PTBP1 RCOR1 SFPQ SKIL SMAD3 SMAD4 SNIP1 SREBF2 SUMO1 TSC22D2 UBE2A UBE2I UBTF ZBTB3 ZNF512B
Entrez ID		6421	7750
HPRD ID		07284	03745
Ensembl ID		ENSG00000116560	ENSG00000121741
Uniprot IDs		A0A384N5Z8 P23246 Q86VG2	A0A024RDS3 A8K126 Q9UBW7
PDB IDs		4WII 4WIJ 4WIK 5WPA 6NCQ
Enriched GO Terms of Interacting Partners?
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