Description |
vascular endothelial growth factor A |
Sp1 transcription factor |
Image |
|
|
GO Annotations |
Cellular Component |
|
|
Molecular Function |
|
|
Biological Process |
|
|
Pathways |
|
|
Drugs |
|
|
Diseases |
|
|
GWAS |
- Adiponectin levels ( 22479202)
- Advanced age-related macular degeneration ( 26691988)
- Age-related macular degeneration ( 23455636 21665990)
- Blood protein levels ( 30072576 29875488)
- Body mass index ( 25673413)
- Chronic kidney disease ( 20383146)
- Coronary artery disease ( 29212778)
- Coronary heart disease ( 22319020)
- Creatinine levels ( 31015462 29124443 29403010)
- Cytokine levels ( 31679650)
- Cytokine network levels (multivariate analysis) ( 31679650)
- Diastolic blood pressure ( 30224653)
- Estimated glomerular filtration rate ( 31015462 29124443 30604766)
- Fasting glucose change (short-term) ( 31263163)
- Glomerular filtration rate ( 27588450 29403010)
- Glomerular filtration rate (creatinine) ( 28452372 26831199)
- Glomerular filtration rate in non diabetics (creatinine) ( 26831199)
- HDL cholesterol ( 24097068)
- HDL cholesterol levels ( 28334899 30698716)
- HDL cholesterol levels in current drinkers ( 30698716)
- HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
- HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
- HDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535)
- Heel bone mineral density ( 30598549)
- Hematocrit ( 27863252)
- Hemoglobin concentration ( 27863252)
- High density lipoprotein cholesterol levels ( 29403010)
- High light scatter reticulocyte percentage of red cells ( 27863252)
- Hyperthyroidism ( 30367059)
- Hyperuricemia ( 29124443)
- Hypothyroidism ( 27182965)
- Interleukin-10 levels ( 27989323)
- Interleukin-12p70 levels ( 27989323)
- Interleukin-13 levels ( 27989323)
- Interleukin-7 levels ( 27989323)
- Medication use (calcium channel blockers) ( 31015401)
- Medication use (HMG CoA reductase inhibitors) ( 31015401)
- Metabolic syndrome ( 31589552)
- Myeloid white cell count ( 27863252)
- Plasma thyroid-stimulating hormone levels ( 28333968)
- Prostate-specific antigen levels ( 28139693)
- Red blood cell count ( 27863252)
- Reticulocyte count ( 27863252)
- Reticulocyte fraction of red cells ( 27863252)
- Serum uric acid levels ( 30993211 29124443)
- Sexual dimorphism in anthropometric traits ( 23754948)
- Thyroid hormone levels ( 23408906)
- Thyroid stimulating hormone levels ( 25743335)
- Triglyceride levels ( 28334899 29403010 30698716)
- Triglyceride levels in current drinkers ( 30698716)
- Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
- Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
- Triglyceride levels x long total sleep time interaction (2df test) ( 31719535)
- Triglycerides ( 24097068 25961943)
- Type 2 diabetes ( 18372903 24509480 30054458 29358691 30297969)
- Urate levels ( 31578528 23263486)
- Urinary albumin-to-creatinine ratio ( 31630189)
- Vascular endothelial growth factor levels ( 26910538 27989323 31217265)
- Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
- Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500)
- Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
- Waist circumference adjusted for BMI in active individuals ( 28448500)
- Waist circumference adjusted for BMI in inactive individuals ( 28448500)
- Waist circumference adjusted for BMI in non-smokers ( 28443625)
- Waist circumference adjusted for body mass index ( 25673412 28448500)
- Waist-hip ratio ( 25673412 20935629)
- Waist-to-hip ratio adjusted for BMI ( 26426971)
- Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
- Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971)
- Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971)
- Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500)
- Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
- Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500)
- Waist-to-hip ratio adjusted for BMI in non-smokers ( 28443625)
- Waist-to-hip ratio adjusted for BMI x sex interaction ( 26426971)
- Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
- Waist-to-hip ratio adjusted for body mass index ( 26785701 25673412 28448500)
- White blood cell count ( 27863252)
|
- Hypospadias (moderate to severe) ( 31856834)
- Mean corpuscular hemoglobin ( 29403010)
- Mean corpuscular volume ( 29403010)
- Neutrophil percentage of white cells ( 27863252)
- Parkinsonism in frontotemporal lobe dementia ( 29724592)
- Percentage gas trapping ( 26030696)
- Progressive supranuclear palsy ( 30089514)
- Red blood cell count ( 27863252)
- Reticulocyte count ( 27863252)
|
Interacting Genes |
32 interacting genes:
ADAMTS1
AKT1
CCN2
CRYAB
ELAVL1
EPHB2
FLT1
FN1
GPC1
HIF1A
HNRNPD
IGFBP7
KDR
LYVE1
MDM2
NRP1
NRP2
PGF
PRRG4
SEMA3F
SP1
SP3
SPARC
TFAP2A
TNXB
U2AF1
UBIAD1
VEGFB
VPS35
VTN
YBX1
YBX3
|
145 interacting genes:
AATF
AHR
AKT1
AR
ARHGAP21
ARNT
ATF7IP
ATF7IP2
BCL11B
BCL6
BCOR
BRCA1
CASP3
CASP6
CASP7
CBX5
CCNA1
CCNA2
CCND1
CD2
CDK1
CDK2
CEBPB
CSNK2A1
CTCFL
CTNNB1
DDX5
DROSHA
E2F1
E2F2
E2F3
EGR1
ELF1
EP300
ESR1
ESR2
ESRRA
ESRRB
ESRRG
ETS1
GABPA
GATA1
GATA3
GATA4
HBZ
HCFC1
HDAC1
HDAC2
HIF1A
HINT1
HLTF
HMGA1
HNF4A
HOXC11
HSPA8
HTT
IL1B
JUN
KIF1A
KLF10
KLF4
KLF6
LDB1
LMO2
MAPK1
MAPK3
MAPK8
MBD1
MEF2C
MEF2D
MIER1
MIS18BP1
MSX1
MTREX
MYC
MYCN
MYOD1
MYOG
NAP1L1
NCOR1
NCOR2
NEPRO
NFKB1
NFKB2
NFYA
NFYB
NFYC
NKX3-1
NOS3
NPM1
NR2F1
NR5A1
NUP62
OGT
PARP1
PER3
PML
POGZ
POU2F1
PPIG
PPP1R13L
PRKCZ
PRKDC
PSIP1
PSMC5
PURA
RARA
RB1
RBBP4
RBL1
REL
RELA
RNF4
RORA
RXRA
SENP6
SF3A1
SHC1
SMAD2
SMAD3
SMAD4
SMARCC1
SMARCC2
SOX10
SOX8
SP3
SP4
SREBF1
SREBF2
SRF
SUB1
TAF4
TAL1
TBP
TLX3
TP53
TP73
TPI1
USP39
VEGFA
VHL
YY1
ZBTB16
ZBTB2
ZBTB7A
|
Entrez ID |
7422 |
6667 |
HPRD ID |
01889 |
01796 |
Ensembl ID |
ENSG00000112715
|
ENSG00000185591
|
Uniprot IDs |
A0A024RD33
A0A024RD37
A0A0Y0IMM4
A2A2V4
P15692
|
P08047
|
PDB IDs |
1BJ1
1CZ8
1FLT
1KAT
1KMX
1MJV
1MKG
1MKK
1QTY
1TZH
1TZI
1VGH
1VPF
1VPP
2FJG
2FJH
2QR0
2VGH
2VPF
3BDY
3P9W
3QTK
3S1B
3S1K
3V2A
4DEQ
4GLN
4GLS
4KZN
4QAF
4WPB
4ZFF
5DN2
5FV1
5FV2
5HHC
5HHD
5O4E
5T89
6BFT
6D3O
|
1SP1
1SP2
1VA1
1VA2
1VA3
|
Enriched GO Terms of Interacting Partners? |
|
|
Tagcloud ? |
|
|
Tagcloud (Difference) ? |
|
|
Tagcloud (Intersection) ? |
|