VASP and TRIM15

Number of citations of the paper that reports this interaction (PubMedID 25450970)
15

Data Source:
BioGRID (protein complementation assay)

		VASP	TRIM15
Description		vasodilator stimulated phosphoprotein	tripartite motif containing 15
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Bicellular Tight Junction Focal Adhesion Actin Cytoskeleton Lamellipodium Membrane Filopodium Membrane Extracellular Exosome
	Molecular Function	Actin Binding Protein Binding Profilin Binding SH3 Domain Binding Cadherin Binding	Protein Binding Zinc Ion Binding
	Biological Process	Neural Tube Closure Axon Guidance Actin Polymerization Or Depolymerization Actin Cytoskeleton Organization Positive Regulation Of Actin Filament Polymerization Cell Junction Assembly Protein Homotetramerization	Mesodermal Cell Fate Determination Positive Regulation Of Type I Interferon Production Innate Immune Response Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of RIG-I Signaling Pathway Negative Regulation Of Intracellular Transport Of Viral Material Negative Regulation Of Viral Release From Host Cell
Pathways		Generation of second messenger molecules Signaling by ROBO receptors Signaling by ROBO receptors Cell-extracellular matrix interactions
Drugs
Diseases
GWAS		Alzheimer's disease or HDL levels (pleiotropy) ( 30805717)	Anger ( 24489884) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Neurociticism ( 29500382) Neuroticism ( 29255261)
Interacting Genes		42 interacting genes: ABI1 ABI2 ABI3 ACTA1 ACTG1 APBB1 APBB1IP CEP43 DMRTB1 DNMBP ENAH ERMAP EVL FAT1 FRS3 FYB1 GSN IQGAP1 LPP NOL3 NR4A1 PFN1 PFN2 PLSCR1 PRKACA PRKG1 PRPF40A RAD51 RAPH1 SAT1 SCGB2A2 SPTA1 TES TRIM15 TRIM9 VCL WAS WASL WWP2 XIRP1 XPO6 ZYX	36 interacting genes: ACD ACTB AXIN1 CFL1 CORO1B CTTN EHMT1 FAM151B FAM161A FBLIM1 FERMT2 FERMT3 GAB1 GTF2E1 IRF5 KEAP1 MED7 MSN MYBL2 NEXN PFN1 PRNP PTK2 PXN RABGEF1 ROCK1 SHC1 SNW1 SYK TAF9B TINF2 TRIM8 UBE2U VASP VCL VIM
Entrez ID		7408	89870
HPRD ID		03415	15551
Ensembl ID		ENSG00000125753	ENSG00000204610
Uniprot IDs		A0A024R0V4 P50552	Q5SRL0 Q9C019
PDB IDs		1EGX 1JNG 1USD 1USE 2PAV 2PBD 3CHW
Enriched GO Terms of Interacting Partners?
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