UTRN and MARCHF5

Number of citations of the paper that reports this interaction (PubMedID 16936636)
156

Data Source:
HPRD (in vivo, in vitro)

		UTRN	MARCHF5
Description		utrophin	membrane associated ring-CH-type finger 5
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytoskeleton Plasma Membrane Dystrophin-associated Glycoprotein Complex Membrane Cell Junction Filopodium Growth Cone Cortical Actin Cytoskeleton Filopodium Membrane Neuromuscular Junction Protein-containing Complex Sarcolemma Postsynaptic Membrane Extracellular Exosome Contractile Ring	Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane
	Molecular Function	Actin Binding Integrin Binding Protein Binding Zinc Ion Binding Vinculin Binding Protein Kinase Binding Actin Filament Binding	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding GTPase Binding
	Biological Process	Positive Regulation Of Cell-matrix Adhesion Muscle Contraction Muscle Organ Development Neuromuscular Junction Development Response To Denervation Involved In Regulation Of Muscle Adaptation Regulation Of Sodium Ion Transmembrane Transporter Activity	Protein Polyubiquitination Protein Autoubiquitination Protein Localization To Mitochondrion Regulation Of Mitochondrial Fission Positive Regulation Of Mitochondrial Fission Negative Regulation Of Cell Aging
Pathways		EGR2 and SOX10-mediated initiation of Schwann cell myelination
Drugs		Zinc
Diseases
GWAS		Loneliness (multivariate analysis) ( 27629369) Multisite chronic pain ( 31194737) Peripheral arterial disease (traffic-related air pollution interaction) ( 27082954) Remission after SSRI treatment in MDD or openness ( 29559929) Response to fenofibrate (triglyceride levels) ( 27002377) Response to mepolizumab in severe asthma ( 29229094) Response to SSRI in MDD or openness ( 29559929)
Interacting Genes		20 interacting genes: ACTA1 ACTN2 CALM1 DAG1 DISC1 DMD DRP2 DTNA DTNB MARCHF5 MARK2 NUP98 PGM5 PRKACA PTEN PTPN12 SASH1 SNTA1 SNTB1 SNTB2	19 interacting genes: AKTIP CREB3 FATE1 FIS1 FUNDC1 MAP1B MFN2 SOD1 TANK UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E3 UBE2I UBE2N UBE2T UBE2W UTRN
Entrez ID		7402	54708
HPRD ID		00547	07909
Ensembl ID		ENSG00000152818	ENSG00000198060
Uniprot IDs		P46939 Q5T097 Q6LBS5	Q9NX47
PDB IDs		1BHD 1QAG
Enriched GO Terms of Interacting Partners?
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