MARCHF5 and FIS1

Number of citations of the paper that reports this interaction (PubMedID 16874301)
135

Data Source:
HPRD (in vivo)

		MARCHF5	FIS1
Description		membrane associated ring-CH-type finger 5	fission, mitochondrial 1
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane	Cell Mitochondrion Mitochondrial Outer Membrane Peroxisome Integral Component Of Peroxisomal Membrane Endoplasmic Reticulum Membrane Integral Component Of Mitochondrial Outer Membrane Protein-containing Complex
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding GTPase Binding	Protein Binding Identical Protein Binding Protein-containing Complex Binding
	Biological Process	Protein Polyubiquitination Protein Autoubiquitination Protein Localization To Mitochondrion Regulation Of Mitochondrial Fission Positive Regulation Of Mitochondrial Fission Negative Regulation Of Cell Aging	Mitochondrial Fission Autophagy Of Mitochondrion Release Of Cytochrome C From Mitochondria Protein Targeting To Mitochondrion Apoptotic Process Positive Regulation Of Cytosolic Calcium Ion Concentration Mitochondrial Fusion Regulation Of Mitochondrion Organization Response To Muscle Activity Peroxisome Fission Response To Nutrient Levels Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Calcium-mediated Signaling Using Intracellular Calcium Source Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Neuron Apoptotic Process Mitochondrial Fragmentation Involved In Apoptotic Process Positive Regulation Of Mitochondrial Calcium Ion Concentration Mitochondrion Morphogenesis Cellular Response To Glucose Stimulus Positive Regulation Of Mitochondrial Fission Positive Regulation Of Protein Targeting To Membrane Cellular Response To Toxic Substance Cellular Response To Peptide Response To Fluoride Cellular Response To Thapsigargin Response To Flavonoid Response To Hypobaric Hypoxia Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways			Class I peroxisomal membrane protein import
Drugs
Diseases
GWAS			Rheumatoid arthritis ( 30891314)
Interacting Genes		19 interacting genes: AKTIP CREB3 FATE1 FIS1 FUNDC1 MAP1B MFN2 SOD1 TANK UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E3 UBE2I UBE2N UBE2T UBE2W UTRN	11 interacting genes: A2M BCAP31 CREB3 DNM1L KASH5 MARCHF5 NOS3 PEX5 TBC1D15 UBC VKORC1
Entrez ID		54708	51024
HPRD ID		07909	12352
Ensembl ID		ENSG00000198060	ENSG00000214253
Uniprot IDs		Q9NX47	Q9Y3D6
PDB IDs			1NZN 1PC2
Enriched GO Terms of Interacting Partners?
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