UTRN and DTNA

Number of citations of the paper that reports this interaction (PubMedID 9701558)
20

Data Source:
BioGRID (far western blotting, far western blotting)
HPRD (in vivo, in vitro)

		UTRN	DTNA
Description		utrophin	dystrobrevin alpha
Image
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytoskeleton Plasma Membrane Dystrophin-associated Glycoprotein Complex Membrane Cell Junction Filopodium Growth Cone Cortical Actin Cytoskeleton Filopodium Membrane Neuromuscular Junction Protein-containing Complex Sarcolemma Postsynaptic Membrane Extracellular Exosome Contractile Ring	Cytoplasm Cell Junction Axon Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Protein-containing Complex Sarcolemma Synapse
	Molecular Function	Actin Binding Integrin Binding Protein Binding Zinc Ion Binding Vinculin Binding Protein Kinase Binding Actin Filament Binding	Protein Binding Zinc Ion Binding PDZ Domain Binding
	Biological Process	Positive Regulation Of Cell-matrix Adhesion Muscle Contraction Muscle Organ Development Neuromuscular Junction Development Response To Denervation Involved In Regulation Of Muscle Adaptation Regulation Of Sodium Ion Transmembrane Transporter Activity	Striated Muscle Contraction Signal Transduction Chemical Synaptic Transmission Neuromuscular Synaptic Transmission
Pathways		EGR2 and SOX10-mediated initiation of Schwann cell myelination
Drugs		Zinc
Diseases
GWAS		Loneliness (multivariate analysis) ( 27629369) Multisite chronic pain ( 31194737) Peripheral arterial disease (traffic-related air pollution interaction) ( 27082954) Remission after SSRI treatment in MDD or openness ( 29559929) Response to fenofibrate (triglyceride levels) ( 27002377) Response to mepolizumab in severe asthma ( 29229094) Response to SSRI in MDD or openness ( 29559929)	Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) Urate levels in overweight individuals ( 25811787)
Interacting Genes		20 interacting genes: ACTA1 ACTN2 CALM1 DAG1 DISC1 DMD DRP2 DTNA DTNB MARCHF5 MARK2 NUP98 PGM5 PRKACA PTEN PTPN12 SASH1 SNTA1 SNTB1 SNTB2	16 interacting genes: ACTA1 DMD DRP2 DTNBP1 GFI1B HMG20A KCNJ12 SNTA1 SNTB1 SNTB2 SNTG1 SNTG2 STAT3 SYNC SYNM UTRN
Entrez ID		7402	1837
HPRD ID		00547	03141
Ensembl ID		ENSG00000152818	ENSG00000134769
Uniprot IDs		P46939 Q5T097 Q6LBS5	A0A024RC32 B7Z3X3 Q9Y4J8
PDB IDs		1BHD 1QAG	2E5R
Enriched GO Terms of Interacting Partners?
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