DTNA and UTRN

Number of citations of the paper that reports this interaction (PubMedID 9701558)
20

Data Source:
BioGRID (far western blotting, far western blotting)
HPRD (in vivo, in vitro)

		DTNA	UTRN
Description		dystrobrevin alpha	utrophin
Image
GO Annotations	Cellular Component	Cytoplasm Cell Junction Axon Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Protein-containing Complex Sarcolemma Synapse	Nucleoplasm Cytoplasm Cytoskeleton Plasma Membrane Dystrophin-associated Glycoprotein Complex Membrane Cell Junction Filopodium Growth Cone Cortical Actin Cytoskeleton Filopodium Membrane Neuromuscular Junction Protein-containing Complex Sarcolemma Postsynaptic Membrane Extracellular Exosome Contractile Ring
	Molecular Function	Protein Binding Zinc Ion Binding PDZ Domain Binding	Actin Binding Integrin Binding Protein Binding Zinc Ion Binding Vinculin Binding Protein Kinase Binding Actin Filament Binding
	Biological Process	Striated Muscle Contraction Signal Transduction Chemical Synaptic Transmission Neuromuscular Synaptic Transmission	Positive Regulation Of Cell-matrix Adhesion Muscle Contraction Muscle Organ Development Neuromuscular Junction Development Response To Denervation Involved In Regulation Of Muscle Adaptation Regulation Of Sodium Ion Transmembrane Transporter Activity
Pathways			EGR2 and SOX10-mediated initiation of Schwann cell myelination
Drugs			Zinc
Diseases
GWAS		Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) Urate levels in overweight individuals ( 25811787)	Loneliness (multivariate analysis) ( 27629369) Multisite chronic pain ( 31194737) Peripheral arterial disease (traffic-related air pollution interaction) ( 27082954) Remission after SSRI treatment in MDD or openness ( 29559929) Response to fenofibrate (triglyceride levels) ( 27002377) Response to mepolizumab in severe asthma ( 29229094) Response to SSRI in MDD or openness ( 29559929)
Interacting Genes		16 interacting genes: ACTA1 DMD DRP2 DTNBP1 GFI1B HMG20A KCNJ12 SNTA1 SNTB1 SNTB2 SNTG1 SNTG2 STAT3 SYNC SYNM UTRN	20 interacting genes: ACTA1 ACTN2 CALM1 DAG1 DISC1 DMD DRP2 DTNA DTNB MARCHF5 MARK2 NUP98 PGM5 PRKACA PTEN PTPN12 SASH1 SNTA1 SNTB1 SNTB2
Entrez ID		1837	7402
HPRD ID		03141	00547
Ensembl ID		ENSG00000134769	ENSG00000152818
Uniprot IDs		A0A024RC32 B7Z3X3 Q9Y4J8	P46939 Q5T097 Q6LBS5
PDB IDs		2E5R	1BHD 1QAG
Enriched GO Terms of Interacting Partners?
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