UBE2G2 and UBE2J2

Number of citations of the paper that reports this interaction (PubMedID 8393731)
166

Data Source:
HPRD (in vivo)

		UBE2G2	UBE2J2
Description		ubiquitin conjugating enzyme E2 G2	ubiquitin conjugating enzyme E2 J2
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GO Annotations	Cellular Component	Endoplasmic Reticulum Cytosol	Ubiquitin Ligase Complex Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Identical Protein Binding Ubiquitin Conjugating Enzyme Activity	ATP Binding Ubiquitin Protein Ligase Binding Ubiquitin Conjugating Enzyme Activity
	Biological Process	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Ubiquitin-dependent ERAD Pathway Cellular Response To Interferon-beta Cellular Protein Catabolic Process Protein K48-linked Ubiquitination Negative Regulation Of Retrograde Protein Transport, ER To Cytosol	Protein Polyubiquitination Response To Unfolded Protein Protein Ubiquitination Ubiquitin-dependent ERAD Pathway Positive Regulation Of Protein Targeting To Mitochondrion
Pathways		Synthesis of active ubiquitin: roles of E1 and E2 enzymes Antigen processing: Ubiquitination & Proteasome degradation	E3 ubiquitin ligases ubiquitinate target proteins Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Inflammatory bowel disease ( 28067908) Systemic lupus erythematosus ( 28714469) Ulcerative colitis ( 28067908)
Interacting Genes		38 interacting genes: AMFR ARL14 BIRC8 CBL CNNM3 CPOX CUL9 ECPAS FARP2 HBS1L KDM2A MDM2 MGRN1 MLLT6 MUL1 NDUFS4 POLR3F PRKN RBX1 RC3H1 RC3H2 RFFL RNF111 RNF146 RNF157 RNF168 RNF26 RNF5 TMEM45B TRIM3 TRIM43 UBA1 UBA6 UBC UBE2J2 UBE3A VAMP8 ZNRF4	17 interacting genes: ATP13A2 FBXO7 HECW1 HERC4 ITCH MDM2 MGRN1 NEDD4L PRKN PUSL1 RNF10 TRIM25 UBA1 UBC UBE2G2 WWP2 XIAP
Entrez ID		7327	118424
HPRD ID		04387	15600
Ensembl ID		ENSG00000184787	ENSG00000160087
Uniprot IDs		P60604	A0A024R075 A6NGS0 Q8N2K1
PDB IDs		2CYX 2KLY 2LXP 3H8K 4LAD	2F4W
Enriched GO Terms of Interacting Partners?
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