UBE2G2 and HBS1L

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		UBE2G2	HBS1L
Description		ubiquitin conjugating enzyme E2 G2	HBS1 like translational GTPase
Image
GO Annotations	Cellular Component	Endoplasmic Reticulum Cytosol	Cytosol Membrane Extracellular Exosome
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Identical Protein Binding Ubiquitin Conjugating Enzyme Activity	Translation Elongation Factor Activity GTPase Activity Protein Binding GTP Binding
	Biological Process	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Ubiquitin-dependent ERAD Pathway Cellular Response To Interferon-beta Cellular Protein Catabolic Process Protein K48-linked Ubiquitination Negative Regulation Of Retrograde Protein Transport, ER To Cytosol	Translation Translational Elongation Signal Transduction Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay
Pathways		Synthesis of active ubiquitin: roles of E1 and E2 enzymes Antigen processing: Ubiquitination & Proteasome degradation	mRNA decay by 3' to 5' exoribonuclease
Drugs
Diseases
GWAS			Aspartate aminotransferase levels ( 29403010) Beta thalassemia/hemoglobin E disease ( 20183929) Cholesterol, total ( 24097068) Eosinophil counts ( 29403010 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252) Fetal hemoglobin levels in sickle cell anemia ( 25372704) Glycated hemoglobin levels ( 24647736) Granulocyte count ( 27863252) HbA2 levels ( 23043469) Hematocrit ( 29403010 27863252 28017375 19862010) Hematological and biochemical traits ( 20139978) Hematological parameters ( 19820697) Hematology traits ( 23263863) Hemoglobin ( 29403010) Hemoglobin A1c levels ( 29403010) Hemoglobin concentration ( 27863252) High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Hodgkin's lymphoma ( 24149102) LDL cholesterol ( 30275531) LDL cholesterol levels ( 28334899) Mean corpuscular hemoglobin ( 23263863 29403010 19853236 28453575 20139978 27863252 28017375 28548082 19862010) Mean corpuscular hemoglobin concentration ( 23263863 29403010 20139978 27863252 28017375) Mean corpuscular volume ( 23263863 29403010 19853236 28453575 20139978 27863252 28017375 19862010) Metabolite levels ( 23823483) Monocyte count ( 27863252) Multiple sclerosis ( 31604244) Myeloid white cell count ( 27863252) Myeloproliferative neoplasms ( 25849990) Neutrophil count ( 27863252) Neutrophil percentage of granulocytes ( 27863252) Other erythrocyte phenotypes ( 19862010) Platelet count ( 26805783 22139419 24026423 29066854 29403010 19853236 22423221 20139978 27863252) Plateletcrit ( 27863252) Red blood cell count ( 29403010 28453575 20139978 27863252 28017375) Red blood cell traits ( 20927387 23935956 23222517) Red cell distribution width ( 27863252) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252) Sum basophil neutrophil counts ( 27863252) Sum eosinophil basophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Total cholesterol levels ( 28334899 30275531) White blood cell count ( 29403010 20139978 27863252) White blood cell types ( 21738478)
Interacting Genes		38 interacting genes: AMFR ARL14 BIRC8 CBL CNNM3 CPOX CUL9 ECPAS FARP2 HBS1L KDM2A MDM2 MGRN1 MLLT6 MUL1 NDUFS4 POLR3F PRKN RBX1 RC3H1 RC3H2 RFFL RNF111 RNF146 RNF157 RNF168 RNF26 RNF5 TMEM45B TRIM3 TRIM43 UBA1 UBA6 UBC UBE2J2 UBE3A VAMP8 ZNRF4	10 interacting genes: APP EXOSC4 EXOSC5 EXOSC6 EXOSC9 MAP3K1 PELO SRPK1 SRPK2 UBE2G2
Entrez ID		7327	10767
HPRD ID		04387	06582
Ensembl ID		ENSG00000184787	ENSG00000112339
Uniprot IDs		P60604	D9YZV0 Q9Y450
PDB IDs		2CYX 2KLY 2LXP 3H8K 4LAD	5LZW 5LZX 5LZY 5LZZ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?