UBE2J2 and MGRN1

Number of citations of the paper that reports this interaction (PubMedID 19549727)
67

Data Source:
BioGRID (two hybrid)

		UBE2J2	MGRN1
Description		ubiquitin conjugating enzyme E2 J2	mahogunin ring finger 1
Image			No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane	Nucleus Cytoplasm Early Endosome Cytosol Plasma Membrane Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	ATP Binding Ubiquitin Protein Ligase Binding Ubiquitin Conjugating Enzyme Activity	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein Polyubiquitination Response To Unfolded Protein Protein Ubiquitination Ubiquitin-dependent ERAD Pathway Positive Regulation Of Protein Targeting To Mitochondrion	Protein Polyubiquitination Protein Monoubiquitination Endosome To Lysosome Transport Protein Ubiquitination Negative Regulation Of CAMP-mediated Signaling Negative Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Smoothened Signaling Pathway
Pathways		E3 ubiquitin ligases ubiquitinate target proteins Antigen processing: Ubiquitination & Proteasome degradation	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 28067908) Systemic lupus erythematosus ( 28714469) Ulcerative colitis ( 28067908)	Milk allergy (maternal genetic effects) ( 29489655)
Interacting Genes		17 interacting genes: ATP13A2 FBXO7 HECW1 HERC4 ITCH MDM2 MGRN1 NEDD4L PRKN PUSL1 RNF10 TRIM25 UBA1 UBC UBE2G2 WWP2 XIAP	13 interacting genes: AMFR TRIM74 TSG101 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2G2 UBE2I UBE2J2 UBE2T UBE2W
Entrez ID		118424	23295
HPRD ID		15600	07397
Ensembl ID		ENSG00000160087	ENSG00000102858
Uniprot IDs		A0A024R075 A6NGS0 Q8N2K1	O60291
PDB IDs		2F4W
Enriched GO Terms of Interacting Partners?
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