TNFRSF4 and SIVA1

Number of citations of the paper that reports this interaction (PubMedID 12478477)
21

Data Source:
HPRD (in vitro)

		TNFRSF4	SIVA1
Description		TNF receptor superfamily member 4	SIVA1 apoptosis inducing factor
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Cell Surface	Nucleoplasm Cytoplasm
	Molecular Function	Virus Receptor Activity Tumor Necrosis Factor-activated Receptor Activity Protein Binding	Virus Receptor Activity Tumor Necrosis Factor Receptor Binding CD27 Receptor Binding Protein Binding Metal Ion Binding
	Biological Process	Inflammatory Response Immune Response Positive Regulation Of B Cell Proliferation Tumor Necrosis Factor-mediated Signaling Pathway T Cell Proliferation Negative Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of Transcription, DNA-templated Viral Entry Into Host Cell Negative Regulation Of Cytokine Secretion Positive Regulation Of Immunoglobulin Secretion	Viral Entry Into Host Cell Extrinsic Apoptotic Signaling Pathway
Pathways		TNFs bind their physiological receptors
Drugs			Zinc
Diseases
GWAS		Inflammatory bowel disease ( 23128233)	Endometrial cancer ( 27135401) Endometrial endometrioid carcinoma ( 27135401)
Interacting Genes		10 interacting genes: NUFIP2 RC3H1 SIVA1 TNFRSF9 TNFSF4 TRAF1 TRAF2 TRAF3 TRAF4 TRAF5	20 interacting genes: ABL2 APP BAG5 BCL2L1 BEX3 CD27 CD4 CDKN2A MEFV NEDD4 NEDD4L PCNA POLR2M PXMP2 RAD18 RHOU SSBP3 TCAP TNFRSF4 UBE2D1
Entrez ID		7293	10572
HPRD ID		02636	16124
Ensembl ID		ENSG00000186827	ENSG00000184990
Uniprot IDs		P43489	O15304
PDB IDs		1D0A 2HEV 2HEY 6OGX 6OKM 6OKN
Enriched GO Terms of Interacting Partners?
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