TRPC4 and ITCH

  • Number of citations of the paper that reports this interaction (PubMedID 17110928)
  • 20
  • Data Source:
  • HPRD (in vivo)

TRPC4

ITCH

Description transient receptor potential cation channel subfamily C member 4 itchy E3 ubiquitin protein ligase
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Age-related macular degeneration ( 23326517)
  • Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653)
  • Mild influenza (H1N1) infection ( 26379185)
  • Obesity-related traits ( 23251661)
  • Smoking initiation ( 30617275)
  • Smoking initiation (ever regular vs never regular) ( 30679032)
  • Tourette's syndrome or obsessive-compulsive disorder ( 25158072)
Interacting Genes 10 interacting genes: DRD2 ITCH ITPR1 ITPR2 ITPR3 MX1 SLC9A3R1 TJP1 TRPC1 TRPC5 103 interacting genes: ARHGEF7 ARID1A ARRB2 ARRDC3 ATN1 BECN1 BIN1 BRAF CBL CBLC CDC34 CEP250 CPSF6 CPSF7 CSNK2A1 CXCR4 CYLD DAZAP1 DTX1 DTX3L ERBB4 EWSR1 FYN GLIS3 GNAI2 HNRNPL HNRNPUL1 JUN JUNB KPNB1 LAPTM5 LITAF LRRK1 MAP2K4 MAPK8 MARVELD2 MLANA N4BP1 NDFIP1 NDFIP2 NEDD9 NFE2 NOTCH1 NUDT21 NUMB PABPC1 PACSIN1 POLR2A POLR2B POLR2C POLR2E POU5F1 PRKACA RASSF5 RIPK1 RNF11 RPAP2 RPAP3 SCNN1A SCNN1B SF1 SGK3 SH3GL1 SH3GL2 SMAD2 SMAD3 SMARCC1 SMARCC2 SMARCE1 SMN1 SNX9 SPART STAM2 SUFU TAB1 TP63 TP73 TRPC4 TRPV1 TRPV4 TXNIP UBAP2 UBAP2L UBC UBE2C UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2G1 UBE2J2 UBE2K UBE2L3 UBE2M UBE2O UBE2Q1 UBE2Q2 UBE2R2 URI1 WBP2
Entrez ID 7223 83737
HPRD ID 09154 07565
Ensembl ID ENSG00000133107 ENSG00000078747
Uniprot IDs Q9UBN4 A0A590UJQ1 Q96J02
PDB IDs 2DMV 2KYK 2NQ3 2P4R 2YSF 3TUG 4ROF 5C7M 5CQ2 5DWS 5DZD 5SXP
Enriched GO Terms of Interacting Partners?
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