C4BPA and FXYD6

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		C4BPA	FXYD6
Description		complement component 4 binding protein alpha	FXYD domain containing ion transport regulator 6
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane Blood Microparticle	Plasma Membrane Glutamatergic Synapse Integral Component Of Postsynaptic Membrane Integral Component Of Presynaptic Membrane
	Molecular Function	RNA Binding Protein Binding	Molecular_function Protein Binding Sodium Channel Regulator Activity Ion Channel Regulator Activity
	Biological Process	Complement Activation, Classical Pathway Response To Symbiotic Bacterium Regulation Of Complement Activation Innate Immune Response Positive Regulation Of Protein Catabolic Process Negative Regulation Of Complement Activation, Classical Pathway Regulation Of Opsonization	Biological_process Ion Transmembrane Transport Regulation Of Cardiac Conduction Regulation Of Sodium Ion Transmembrane Transporter Activity
Pathways		Regulation of Complement cascade	Ion homeostasis Ion transport by P-type ATPases
Drugs		Zinc Copper
Diseases		Complement regulatory protein defects, including the following six diseases: C1 inhibitor deficiency (hereditary angioedema); C4 binding protein alpha deficiency; C4 binding protein beta deficiency; Factor I deficiency; Decay-accelerating factor (CD55) deficiency; CD59 deficiency
GWAS		Blood protein levels ( 30072576 29875488) C4b binding protein levels ( 20212171) Mean platelet volume ( 27863252) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Venous thromboembolism ( 31420334 31676865)	Hippocampal volume in Alzheimer's disease dementia ( 29274321) Myopia ( 27182965)
Interacting Genes		9 interacting genes: APCS BMPR2 FXYD6 GIT2 GTF2I LBP LRP1 PROS1 SMARCD1	15 interacting genes: BCAR1 C4BPA CCDC90B CREB3 CREB3L1 GDF9 HAUS2 LMNA PPP1CC RBM48 SLC35E1 TLE1 TP53 TRIM27 UNC119
Entrez ID		722	53826
HPRD ID		00403	09456
Ensembl ID		ENSG00000123838	ENSG00000137726
Uniprot IDs		P04003	A0A024R3J8 Q9H0Q3
PDB IDs		2A55 4B0F 5HYP 5HYT 5HYU 5HZP 5I0Q
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?