FXYD6 and HAUS2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		FXYD6	HAUS2
Description		FXYD domain containing ion transport regulator 6	HAUS augmin like complex subunit 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Glutamatergic Synapse Integral Component Of Postsynaptic Membrane Integral Component Of Presynaptic Membrane	Centrosome Cytosol Spindle Microtubule HAUS Complex
	Molecular Function	Molecular_function Protein Binding Sodium Channel Regulator Activity Ion Channel Regulator Activity	Molecular_function Protein Binding
	Biological Process	Biological_process Ion Transmembrane Transport Regulation Of Cardiac Conduction Regulation Of Sodium Ion Transmembrane Transporter Activity	G2/M Transition Of Mitotic Cell Cycle Centrosome Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Spindle Assembly Cell Division Ciliary Basal Body-plasma Membrane Docking
Pathways		Ion homeostasis Ion transport by P-type ATPases	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Hippocampal volume in Alzheimer's disease dementia ( 29274321) Myopia ( 27182965)	Bipolar disorder ( 31043756) Glucose homeostasis traits ( 25524916)
Interacting Genes		15 interacting genes: BCAR1 C4BPA CCDC90B CREB3 CREB3L1 GDF9 HAUS2 LMNA PPP1CC RBM48 SLC35E1 TLE1 TP53 TRIM27 UNC119	2 interacting genes: FXYD6 MAPK6
Entrez ID		53826	55142
HPRD ID		09456	07675
Ensembl ID		ENSG00000137726	ENSG00000137814
Uniprot IDs		A0A024R3J8 Q9H0Q3	A0A024R9M5 A0A024R9P0 H3BP16 Q9NVX0
PDB IDs
Enriched GO Terms of Interacting Partners?
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