TPM1 and PKD2

  • Number of citations of the paper that reports this interaction (PubMedID 12527301)
  • 20
  • Data Source:
  • HPRD (in vitro, in vivo, two hybrid)

TPM1

PKD2

Description tropomyosin 1 polycystin 2, transient receptor potential cation channel
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Diverticular disease ( 30177863)
  • Estimated glomerular filtration rate ( 31451708)
  • HDL cholesterol levels in current drinkers ( 30698716)
  • HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Impaired insulin sensitivity in response to n-3 PUFA supplementation ( 31779001)
  • Mean platelet volume ( 19820697 27863252)
  • Orofacial clefts ( 22863734)
  • Parkinson's disease (familial, age at onset) ( 27402877)
  • Platelet count ( 22139419 27863252)
  • Platelet distribution width ( 27863252)
  • Pulse pressure ( 27841878)
Interacting Genes 21 interacting genes: ACTB C1orf216 CAGE1 EGFR EPB41 GOLGA2 IFIT3 JUN KXD1 MAD1L1 NEB NOD2 PKD2 S100A2 SYCE1 TFPT TMOD2 TNNT1 TNNT2 TPM2 TPM4 17 interacting genes: ACTN2 CD2AP DIAPH1 HAX1 KRT40 KRTAP10-3 KRTAP10-8 LMNA MAGEA8 PACS1 PACS2 PKD1 PLSCR1 PTPRG TNNI3 TPM1 TRPC1
Entrez ID 7168 5311
HPRD ID 01839 01437
Ensembl ID ENSG00000140416 ENSG00000118762
Uniprot IDs A0A024R5W6 A0A0K0K1I0 B7Z596 B7Z722 D9YZV4 D9YZV5 D9YZV7 F5H7S3 H0YK48 H7BYY1 O15513 P09493 Q13563 Q9UEU6
PDB IDs 3MUD 5KHT 2KLD 2KLE 2KQ6 2Y4Q 3HRN 3HRO 5K47 5MKE 5MKF 5T4D 6A70 6D1W 6T9N 6T9O
Enriched GO Terms of Interacting Partners?
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