TNFAIP1 and SVIL

Number of citations of the paper that reports this interaction (PubMedID 20309963)
26

Data Source:
BioGRID (two hybrid)

		TNFAIP1	SVIL
Description		TNF alpha induced protein 1	supervillin
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endosome Cul3-RING Ubiquitin Ligase Complex	Podosome Nucleus Cytoplasm Cytosol Plasma Membrane Focal Adhesion Actin Cytoskeleton Midbody Cleavage Furrow Microtubule Minus-end Costamere Invadopodium
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding GTP-Rho Binding Identical Protein Binding	Protein Binding Actin Filament Binding
	Biological Process	DNA Replication Apoptotic Process Immune Response Cell Migration Protein Ubiquitination Negative Regulation Of Rho Protein Signal Transduction Stress Fiber Assembly Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of DNA Replication Protein Homooligomerization	Cytoskeleton Organization Skeletal Muscle Tissue Development Positive Regulation Of Cytokinesis
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 29875488) Low density lipoprotein cholesterol levels ( 29403010) Osteoprotegerin levels ( 25080503)	Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Bone fracture in osteoporosis ( 28580392) Estimated glomerular filtration rate ( 31152163) Lung function (FEV1/FVC) ( 28166213) Metabolite levels ( 23823483) Neurofibrillary tangles ( 25188341) Normalized brain volume ( 19010793) Platelet thrombus formation ( 22550155)
Interacting Genes		22 interacting genes: ARMC7 ARNT CAPN7 CARD9 CSNK2B DAPP1 EPHA2 EPM2AIP1 EXOSC5 HAT1 KDM1A POLR1C PSMA1 RHOA RHOB RIN3 SMARCB1 STK16 SUV39H1 SVIL ZDHHC17 ZMYND19	36 interacting genes: AR ATRX BUB1 CENPF DYNLT1 ESR1 FLNA HAX1 HMMR HSP90AA1 ITGB3BP KIF14 KIF22 KIFC3 KMT2A KRT18 LMNA LMNB2 LUC7L2 MIF4GD MPHOSPH9 MRTFB NME2 NR3C1 ODF2 P2RX7 PAN3 PCNX3 PPARG SH3PXD2A STARD9 TGFB1I1 TNFAIP1 TRIP6 UXT YWHAG
Entrez ID		7126	6840
HPRD ID		01856	04992
Ensembl ID		ENSG00000109079	ENSG00000197321
Uniprot IDs		Q13829	O95425 Q569J5
PDB IDs			2K6M 2K6N
Enriched GO Terms of Interacting Partners?
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