SVIL and TNFAIP1

Number of citations of the paper that reports this interaction (PubMedID 20309963)
26

Data Source:
BioGRID (two hybrid)

		SVIL	TNFAIP1
Description		supervillin	TNF alpha induced protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Podosome Nucleus Cytoplasm Cytosol Plasma Membrane Focal Adhesion Actin Cytoskeleton Midbody Cleavage Furrow Microtubule Minus-end Costamere Invadopodium	Nucleus Cytoplasm Endosome Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	Protein Binding Actin Filament Binding	Ubiquitin-protein Transferase Activity Protein Binding GTP-Rho Binding Identical Protein Binding
	Biological Process	Cytoskeleton Organization Skeletal Muscle Tissue Development Positive Regulation Of Cytokinesis	DNA Replication Apoptotic Process Immune Response Cell Migration Protein Ubiquitination Negative Regulation Of Rho Protein Signal Transduction Stress Fiber Assembly Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of DNA Replication Protein Homooligomerization
Pathways
Drugs
Diseases
GWAS		Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Bone fracture in osteoporosis ( 28580392) Estimated glomerular filtration rate ( 31152163) Lung function (FEV1/FVC) ( 28166213) Metabolite levels ( 23823483) Neurofibrillary tangles ( 25188341) Normalized brain volume ( 19010793) Platelet thrombus formation ( 22550155)	Blood protein levels ( 29875488) Low density lipoprotein cholesterol levels ( 29403010) Osteoprotegerin levels ( 25080503)
Interacting Genes		36 interacting genes: AR ATRX BUB1 CENPF DYNLT1 ESR1 FLNA HAX1 HMMR HSP90AA1 ITGB3BP KIF14 KIF22 KIFC3 KMT2A KRT18 LMNA LMNB2 LUC7L2 MIF4GD MPHOSPH9 MRTFB NME2 NR3C1 ODF2 P2RX7 PAN3 PCNX3 PPARG SH3PXD2A STARD9 TGFB1I1 TNFAIP1 TRIP6 UXT YWHAG	22 interacting genes: ARMC7 ARNT CAPN7 CARD9 CSNK2B DAPP1 EPHA2 EPM2AIP1 EXOSC5 HAT1 KDM1A POLR1C PSMA1 RHOA RHOB RIN3 SMARCB1 STK16 SUV39H1 SVIL ZDHHC17 ZMYND19
Entrez ID		6840	7126
HPRD ID		04992	01856
Ensembl ID		ENSG00000197321	ENSG00000109079
Uniprot IDs		O95425 Q569J5	Q13829
PDB IDs		2K6M 2K6N
Enriched GO Terms of Interacting Partners?
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